PDF(Pubmed)
Abstract：
BACKGROUND: Obesity is a major public health concern associated with various health problems, including respiratory impairment. Bioelectrical impedance (BIA) is used in health screening to assess body fat. However, there is no consensus in healthcare on how body fat should be assessed in relation to lung function. In this study, we aimed to investigate how BIA in relation to waist circumference contribute, using data from a large Swedish population study.
METHODS: A total of 17,097 participants (aged 45-75 years) were included in the study. The relationships between fat mass, waist circumference, and lung function were analysed using weighted quantile sum regression.
RESULTS: Increased fat mass was significantly associated with decreased lung function (FEV1, FVC) in both sexes. Also, the influence of trunk fat and waist circumference on FVC and FEV1 differed by sex: in males, waist circumference and trunk fat had nearly equal importance for FVC (variable weights of 0.42 and 0.41), whereas in females, trunk fat was significantly more important (variable weights 0.84 and 0.14). For FEV1, waist circumference was more important in males, while trunk fat was more significant in females (variable weights male 0.68 and 0.28 and 0.23 and 0.77 in female).
CONCLUSIONS: Our results suggest that trunk fat should be considered when assessing the impact of adipose tissue on lung function and should potentially be included in the health controls.
METHODS: A total of 17,097 participants (aged 45-75 years) were included in the study. The relationships between fat mass, waist circumference, and lung function were analysed using weighted quantile sum regression.
RESULTS: Increased fat mass was significantly associated with decreased lung function (FEV1, FVC) in both sexes. Also, the influence of trunk fat and waist circumference on FVC and FEV1 differed by sex: in males, waist circumference and trunk fat had nearly equal importance for FVC (variable weights of 0.42 and 0.41), whereas in females, trunk fat was significantly more important (variable weights 0.84 and 0.14). For FEV1, waist circumference was more important in males, while trunk fat was more significant in females (variable weights male 0.68 and 0.28 and 0.23 and 0.77 in female).
CONCLUSIONS: Our results suggest that trunk fat should be considered when assessing the impact of adipose tissue on lung function and should potentially be included in the health controls.
摘要：
背景：肥胖是与各种健康问题相关的主要公共卫生问题，包括呼吸损伤。生物电阻抗（BIA）用于健康筛查以评估体内脂肪。然而,在如何评估身体脂肪与肺功能的关系方面，医疗保健领域没有达成共识。在这项研究中,我们的目的是调查BIA与腰围的关系，使用来自瑞典大型人口研究的数据。
方法：共有17,097名参与者（45-75岁）被纳入研究。脂肪量之间的关系，腰围,使用加权分位数和回归分析肺功能。
结果：男女脂肪量增加与肺功能（FEV1、FVC）下降显著相关。此外，躯干脂肪和腰围对FVC和FEV1的影响因性别而异：在男性中，腰围和躯干脂肪对FVC的重要性几乎相同（可变重量为0.42和0.41），而在女性中，躯干脂肪明显更为重要（可变体重0.84和0.14）。对于FEV1，腰围在男性中更为重要，而躯干脂肪在女性中更显著(可变体重男性为0.68和0.28，女性为0.23和0.77)。
结论：我们的结果表明，在评估脂肪组织对肺功能的影响时，应考虑躯干脂肪，并可能包括在健康对照中。
方法：共有17,097名参与者（45-75岁）被纳入研究。脂肪量之间的关系，腰围,使用加权分位数和回归分析肺功能。
结果：男女脂肪量增加与肺功能（FEV1、FVC）下降显著相关。此外，躯干脂肪和腰围对FVC和FEV1的影响因性别而异：在男性中，腰围和躯干脂肪对FVC的重要性几乎相同（可变重量为0.42和0.41），而在女性中，躯干脂肪明显更为重要（可变体重0.84和0.14）。对于FEV1，腰围在男性中更为重要，而躯干脂肪在女性中更显著(可变体重男性为0.68和0.28，女性为0.23和0.77)。
结论：我们的结果表明，在评估脂肪组织对肺功能的影响时，应考虑躯干脂肪，并可能包括在健康对照中。
