Abstract：
In cells, proteins are synthesized, function, and degraded (dead). Protein synthesis (spring) is important for the life of proteins. However, how proteins die is equally important for organisms. Proteases are secreted from cells and used as nutrients to break down external proteins. Proteases degrade unwanted and harmful cellular proteins. In eukaryotes, a large enzyme complex called the proteasome is primarily responsible for cellular protein degradation. Prokaryotes, such as bacteria, have similar protein degradation systems. In this review, we describe the structure and function of the ClpXP complex in the degradation system, which is an ATP-dependent protease in bacterial cells, with a particular focus on ClpP.
摘要：
在细胞中，蛋白质是合成的，函数,退化（死亡）。蛋白质合成（弹簧）对于蛋白质的生命很重要。然而,蛋白质如何死亡对生物体同样重要。蛋白酶从细胞中分泌并用作分解外部蛋白质的营养物。蛋白酶降解不需要的和有害的细胞蛋白质。在真核生物中,一种称为蛋白酶体的大型酶复合物主要负责细胞蛋白质的降解。原核生物,如细菌，有类似的蛋白质降解系统。在这次审查中,我们描述了ClpXP复合物在降解系统中的结构和功能，这是细菌细胞中的ATP依赖性蛋白酶，特别关注ClpP。
