Abstract：
Laboratory algorithms using Acid Fast Bacilli (AFB) staining and Mycobacterium tuberculosis (Mtb) polymerase chain reaction (PCR) are often used to remove isolation precautions. A retrospective case review of 52 patients with culture confirmed pulmonary Mtb revealed 4 subjects with negative sputum AFB smears and negative Mtb PCRs. All had significant risk factors for Mtb and had a positive interferon gamma release assay. A negative PCR test result does not exclude an Mtb diagnosis.
摘要：
使用耐酸杆菌（AFB）染色和结核分枝杆菌（Mtb）聚合酶链反应（PCR）的实验室算法通常用于消除分离预防措施。对52例培养证实为肺Mtb的患者的回顾性病例回顾显示，有4例痰AFB涂片阴性和MtbPCR阴性的受试者。所有患者都有明显的Mtb危险因素，并且干扰素γ释放试验呈阳性。PCR检测结果阴性并不排除Mtb诊断。
