{Reference Type}: Journal Article
{Title}: Evaluating the Role of Mycobacterium Tuberculosis PCR in Ruling Out Active Tuberculosis.
{Author}: Rogers I;Barron MA;
{Journal}: Am J Infect Control
{Volume}: 0
{Issue}: 0
{Year}: 2024 Jul 2
{Factor}: 4.303
{DOI}: 10.1016/j.ajic.2024.06.023
{Abstract}: Laboratory algorithms using Acid Fast Bacilli (AFB) staining and Mycobacterium tuberculosis (Mtb) polymerase chain reaction (PCR) are often used to remove isolation precautions. A retrospective case review of 52 patients with culture confirmed pulmonary Mtb revealed 4 subjects with negative sputum AFB smears and negative Mtb PCRs. All had significant risk factors for Mtb and had a positive interferon gamma release assay. A negative PCR test result does not exclude an Mtb diagnosis.