METHODS: This ambidirectional cohort study was conducted in Tianjin, China, from 2017 to 2020, and children\'s regular medical check-up data from birth to 24 months were retrospectively collected. The growth models were used to fit BMI z-score trajectories for children aged 0-24 months. Crossover analysis and interaction model were used to explore the interaction of influencing factors.
RESULTS: We analyzed the growth trajectories of 3217 children, of these, 1493 children with complete follow-up data were included in the influencing factors analysis. Trajectories and parental prepregnancy BMI (ppBMI) were independent factors influencing children\'s body composition. When paternal ppBMI ≥24 kg/m2, regardless of maternal ppBMI, the risk of overweight and obesity in senior-class children was increased. The high trajectories played a partial mediating role in the association between paternal ppBMI and body composition in preschool children.
CONCLUSIONS: BMI growth in children aged 0-24 months can be divided into three latent trajectories: low, middle, and high. These trajectories and parental ppBMI were independent and interactive factors influencing children\'s body composition. The high trajectories played a partial mediating role in the association between paternal ppBMI and body composition in preschool children. It is necessary to pay attention to the BMI growth level of children aged 0-24 months, which plays an important role in the development of body fat in the future.
方法:这项双向队列研究在天津进行,中国,从2017年到2020年,回顾性收集了儿童从出生到24个月的常规体检数据.生长模型用于拟合0-24个月儿童的BMIz评分轨迹。采用交叉分析和交互作用模型探讨影响因素的交互作用。
结果:我们分析了3217名儿童的成长轨迹,其中,1493名有完整随访数据的儿童纳入影响因素分析。运动轨迹和父母孕前BMI(ppBMI)是影响儿童体成分的独立因素。当父亲ppBMI≥24kg/m2时,无论母亲ppBMI如何,高年级儿童超重和肥胖的风险增加.在学龄前儿童中,高轨迹在父系ppBMI与身体成分之间的关联中起部分中介作用。
结论:0-24个月儿童的BMI增长可分为三个潜在轨迹:低,中间,和高。这些轨迹和父母ppBMI是影响儿童身体成分的独立和互动因素。在学龄前儿童中,高轨迹在父系ppBMI与身体成分之间的关联中起部分中介作用。有必要关注0-24个月儿童的BMI增长水平,这在未来身体脂肪的发展中起着重要作用。