Abstract：
BACKGROUND: Down syndrome is associated with an increased risk for otitis media with effusion (OME), a childhood condition in which fluid accumulates in the middle ear, potentially leading to hearing loss. The American Academy of Pediatrics Down syndrome guidelines and the American Academy of Otolaryngology - Head and Neck Surgery OME guidelines recommend hearing testing to assess the hearing status of children with Down syndrome diagnosed with OME.
METHODS: Through an Institutional Review Board approved retrospective chart review at Children\'s Mercy, this project assessed how clinical factors affect the frequency in which children with Down syndrome receive hearing testing after diagnosis of OME. The study included data from all children with Down syndrome between 1 and 8 years old diagnosed with OME in the Down syndrome, general pediatrics, and otolaryngology clinics between 2018 and 2020. Demographics and clinical factors, including clinic setting, were collected.
RESULTS: Of the 124 patients identified, 91.1 % were diagnosed with OME in the otolaryngology clinic and 33.1 % received hearing testing. While most diagnoses occurred in the otolaryngology clinic, a higher proportion of hearing testing at the time of diagnosis occurred in the Down syndrome clinic. This could be explained by the fact that the Down syndrome clinic is a multidisciplinary clinic, where yearly visits include hearing screening. Bivariate analysis using chi-square or Fisher\'s tests showed that clinic setting had a significant association (p-value <0.001) with hearing testing. However, logistic regression depicted all clinical factors had an insignificant effect on hearing testing at 5 % significance.
CONCLUSIONS: While results indicate hearing testing is largely not performed to assess OME early in otolaryngology clinics, they may be used to assess intervention efficacy post-diagnosis. Results point to the importance of Down syndrome clinics in early diagnosis of hearing loss leading to timely referrals to otolaryngology clinics which diagnose and manage OME in children with Down syndrome.
METHODS: Through an Institutional Review Board approved retrospective chart review at Children\'s Mercy, this project assessed how clinical factors affect the frequency in which children with Down syndrome receive hearing testing after diagnosis of OME. The study included data from all children with Down syndrome between 1 and 8 years old diagnosed with OME in the Down syndrome, general pediatrics, and otolaryngology clinics between 2018 and 2020. Demographics and clinical factors, including clinic setting, were collected.
RESULTS: Of the 124 patients identified, 91.1 % were diagnosed with OME in the otolaryngology clinic and 33.1 % received hearing testing. While most diagnoses occurred in the otolaryngology clinic, a higher proportion of hearing testing at the time of diagnosis occurred in the Down syndrome clinic. This could be explained by the fact that the Down syndrome clinic is a multidisciplinary clinic, where yearly visits include hearing screening. Bivariate analysis using chi-square or Fisher\'s tests showed that clinic setting had a significant association (p-value <0.001) with hearing testing. However, logistic regression depicted all clinical factors had an insignificant effect on hearing testing at 5 % significance.
CONCLUSIONS: While results indicate hearing testing is largely not performed to assess OME early in otolaryngology clinics, they may be used to assess intervention efficacy post-diagnosis. Results point to the importance of Down syndrome clinics in early diagnosis of hearing loss leading to timely referrals to otolaryngology clinics which diagnose and manage OME in children with Down syndrome.
摘要：
背景：唐氏综合征与渗出性中耳炎（OME）的风险增加有关，一种童年的情况，液体积聚在中耳，可能导致听力损失。美国儿科学会唐氏综合症指南和美国耳鼻咽喉科学会-头颈外科OME指南建议进行听力测试，以评估诊断为OME的唐氏综合症儿童的听力状态。
方法：通过机构审查委员会批准的儿童慈悲回顾性图表审查，本项目评估了临床因素如何影响唐氏综合征患儿在确诊OME后接受听力检测的频率.该研究包括所有1至8岁的唐氏综合征儿童的数据，这些儿童被诊断为唐氏综合征中的OME，普通儿科,和耳鼻喉科诊所在2018年至2020年之间。人口统计学和临床因素，包括诊所设置，被收集。
结果：在确定的124例患者中，91.1％的人在耳鼻咽喉科诊所被诊断为OME，33.1％的人接受了听力测试。虽然大多数诊断发生在耳鼻喉科诊所，在唐氏综合征诊所中,诊断时听力检测的比例较高.这可以解释为唐氏综合症诊所是一个多学科诊所，每年的访问包括听力筛查。使用卡方检验或Fisher检验的双变量分析表明，临床设置与听力测试具有显着相关性（p值<0.001）。然而,logistic回归显示,所有临床因素对听力测试的影响不显著,显著性为5%.
结论：虽然结果表明听力测试在耳鼻咽喉科诊所早期没有进行评估OME，它们可用于评估诊断后的干预效果.结果指出唐氏综合征诊所在听力损失的早期诊断中的重要性，导致及时转诊至耳鼻喉科诊所，以诊断和管理唐氏综合征儿童的OME。
方法：通过机构审查委员会批准的儿童慈悲回顾性图表审查，本项目评估了临床因素如何影响唐氏综合征患儿在确诊OME后接受听力检测的频率.该研究包括所有1至8岁的唐氏综合征儿童的数据，这些儿童被诊断为唐氏综合征中的OME，普通儿科,和耳鼻喉科诊所在2018年至2020年之间。人口统计学和临床因素，包括诊所设置，被收集。
结果：在确定的124例患者中，91.1％的人在耳鼻咽喉科诊所被诊断为OME，33.1％的人接受了听力测试。虽然大多数诊断发生在耳鼻喉科诊所，在唐氏综合征诊所中,诊断时听力检测的比例较高.这可以解释为唐氏综合症诊所是一个多学科诊所，每年的访问包括听力筛查。使用卡方检验或Fisher检验的双变量分析表明，临床设置与听力测试具有显着相关性（p值<0.001）。然而,logistic回归显示,所有临床因素对听力测试的影响不显著,显著性为5%.
结论：虽然结果表明听力测试在耳鼻咽喉科诊所早期没有进行评估OME，它们可用于评估诊断后的干预效果.结果指出唐氏综合征诊所在听力损失的早期诊断中的重要性，导致及时转诊至耳鼻喉科诊所，以诊断和管理唐氏综合征儿童的OME。
