Abstract：
BACKGROUND: Patients with Brugada syndrome (BrS) face an increased risk of ventricular arrhythmias and sudden cardiac death. Implantable cardiac monitors (ICMs) have emerged as effective tools for detecting arrhythmias in BrS. Technological advancements, including temperature sensors and improved subcutaneous electrocardiogram (subECG) signal quality, hold promise for further enhancing their utility in this population.
RESULTS: We present a case of a 40-year-old man exhibiting a BrS type 2 pattern on 12-lead ECG, who underwent ICM insertion (BIOMONITOR IIIm, BIOTRONIK) due to drug-induced BrS type 1 pattern and a history of syncope, with a negative response to programmed ventricular stimulation. The device contains an integrated temperature sensor and can transmit daily vital data, such as mean heart rate and physical activity. Several months later, remote alerts indicated a temperature increase, along with transmitted subECGs suggesting a fever-induced BrS type 1 pattern. The patient was promptly advised to commence antipyretic therapy. Over the following days, remotely monitored parameters showed decreases in mean temperature, physical activity, and mean heart rate, without further recurrence of abnormal subECGs.
CONCLUSIONS: ICMs offer valuable insights beyond arrhythmia detection in BrS. Early detection of fever using embedded temperature sensors may improve patient management, while continuous subECG morphological analysis has the potential to enhance risk stratification in BrS patients.
RESULTS: We present a case of a 40-year-old man exhibiting a BrS type 2 pattern on 12-lead ECG, who underwent ICM insertion (BIOMONITOR IIIm, BIOTRONIK) due to drug-induced BrS type 1 pattern and a history of syncope, with a negative response to programmed ventricular stimulation. The device contains an integrated temperature sensor and can transmit daily vital data, such as mean heart rate and physical activity. Several months later, remote alerts indicated a temperature increase, along with transmitted subECGs suggesting a fever-induced BrS type 1 pattern. The patient was promptly advised to commence antipyretic therapy. Over the following days, remotely monitored parameters showed decreases in mean temperature, physical activity, and mean heart rate, without further recurrence of abnormal subECGs.
CONCLUSIONS: ICMs offer valuable insights beyond arrhythmia detection in BrS. Early detection of fever using embedded temperature sensors may improve patient management, while continuous subECG morphological analysis has the potential to enhance risk stratification in BrS patients.
摘要：
背景：Brugada综合征（BrS）患者面临室性心律失常和心源性猝死的风险增加。植入式心脏监测仪（ICM）已成为检测BrS心律失常的有效工具。技术进步,包括温度传感器和改进的皮下心电图（subECG）信号质量，有希望进一步提高它们在这一人群中的效用。
结果：我们介绍了一例40岁男性在12导联心电图上表现出BrS2型模式，谁接受了ICM插入(生物监测器IIIm，BIOTRONIK）由于药物诱导的BrS1型模式和晕厥病史，对编程的心室刺激有负面反应。该设备包含一个集成的温度传感器，可以传输日常生命数据，比如平均心率和体力活动。几个月后,远程警报指示温度升高，以及传播的亚ECG，表明发烧诱发的BrS1型模式。患者被及时建议开始退热治疗。在接下来的几天里，远程监测参数显示平均温度下降，身体活动,和平均心率，无异常亚心电图的进一步复发。
结论：ICMs在BrS的心律失常检测中提供了有价值的见解。使用嵌入式温度传感器早期检测发热可以改善患者管理，而连续亚ECG形态学分析有可能增强BrS患者的风险分层。
结果：我们介绍了一例40岁男性在12导联心电图上表现出BrS2型模式，谁接受了ICM插入(生物监测器IIIm，BIOTRONIK）由于药物诱导的BrS1型模式和晕厥病史，对编程的心室刺激有负面反应。该设备包含一个集成的温度传感器，可以传输日常生命数据，比如平均心率和体力活动。几个月后,远程警报指示温度升高，以及传播的亚ECG，表明发烧诱发的BrS1型模式。患者被及时建议开始退热治疗。在接下来的几天里，远程监测参数显示平均温度下降，身体活动,和平均心率，无异常亚心电图的进一步复发。
结论：ICMs在BrS的心律失常检测中提供了有价值的见解。使用嵌入式温度传感器早期检测发热可以改善患者管理，而连续亚ECG形态学分析有可能增强BrS患者的风险分层。
