{Reference Type}: Journal Article
{Title}: Temperature and ST-segment morphology remote monitoring: new perspectives for implantable cardiac monitors in Brugada syndrome.
{Author}: Iacopino S;Sorrenti P;Fabiano E;Colella J;Vilio AD;Statuto G;Filannino P;Artale P;Giacopelli D;Peluso G;Fabiano G;Campagna G;Cecchini E;Petretta A;
{Journal}: Pacing Clin Electrophysiol
{Volume}: 47
{Issue}: 8
{Year}: 2024 Aug 4
{Factor}: 1.912
{DOI}: 10.1111/pace.15042
{Abstract}: <B>BACKGROUND: </B>Patients with Brugada syndrome (BrS) face an increased risk of ventricular arrhythmias and sudden cardiac death. Implantable cardiac monitors (ICMs) have emerged as effective tools for detecting arrhythmias in BrS. Technological advancements, including temperature sensors and improved subcutaneous electrocardiogram (subECG) signal quality, hold promise for further enhancing their utility in this population.<BR><B>RESULTS: </B>We present a case of a 40-year-old man exhibiting a BrS type 2 pattern on 12-lead ECG, who underwent ICM insertion (BIOMONITOR IIIm, BIOTRONIK) due to drug-induced BrS type 1 pattern and a history of syncope, with a negative response to programmed ventricular stimulation. The device contains an integrated temperature sensor and can transmit daily vital data, such as mean heart rate and physical activity. Several months later, remote alerts indicated a temperature increase, along with transmitted subECGs suggesting a fever-induced BrS type 1 pattern. The patient was promptly advised to commence antipyretic therapy. Over the following days, remotely monitored parameters showed decreases in mean temperature, physical activity, and mean heart rate, without further recurrence of abnormal subECGs.<BR><B>CONCLUSIONS: </B>ICMs offer valuable insights beyond arrhythmia detection in BrS. Early detection of fever using embedded temperature sensors may improve patient management, while continuous subECG morphological analysis has the potential to enhance risk stratification in BrS patients.