Abstract：
In the modern world, anyone is susceptible to the effects of stress, regardless of age, gender, culture, and social status. Stress at an early age accelerates long-term changes in the functional properties underlying emotional perception and therefore may alter the stress response later in life. Unfortunately, the interdisciplinary approach in stress research emphasised the study of stress phenomenon in the development of this or that pathology or manifestation of appropriate reactions under the influence of this or that factor, i.e. the study of a particular case, which did not significantly affect the conceptual level of interpretation of the stress phenomenon as such. Moreover, we did not come across any publications interpreting the pathogenesis of the development of the classical triad of stress, confirming, or refuting its validity. In this study, we evaluated the effect of nootropic drugs - polypeptides of cattle cerebral cortex and methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline on the behaviour of rat offspring under conditions of maternal deprivation. The drug affects processes related to memory formation and learning, enhances attention during learning and analysis of information, improves adaptation of the organism to hypoxia, cerebral ischaemia, anaesthesia and other damaging effects. As a result of the conducted study against the background of early postnatal maternal deprivation and the use of such drugs as methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline and polypeptides of cattle cerebral it was noted that the latter drug showed the greatest effectiveness as a means of compensating the reaction to chronic stress under conditions of maternal deprivation.
摘要：
在现代世界,任何人都容易受到压力的影响，不管年龄,性别,文化,和社会地位。早期的压力会加速情绪感知基础功能特性的长期变化，因此可能会在以后的生活中改变应激反应。不幸的是,压力研究中的跨学科方法强调了在这种或那种病理或在这种或那种因素的影响下的适当反应的表现的发展中对压力现象的研究，即对特定案例的研究，这并没有显着影响对压力现象的概念解释水平。此外，我们没有遇到任何解释经典三合会压力发展的发病机理的出版物，确认,或驳斥其有效性。在这项研究中,在母性剥夺条件下，我们评估了促智药-牛大脑皮质多肽和甲氨酰-谷氨酰-组氨酸-苯丙氨酰-氨酰-甘氨酰-脯氨酸对大鼠后代行为的影响。该药物影响与记忆形成和学习有关的过程，在信息的学习和分析过程中提高注意力，提高生物体对缺氧的适应性，脑缺血,麻醉和其他破坏性影响。作为在早期产后产妇剥夺的背景下进行的研究的结果，以及使用甲硫氨酰基-谷氨酰-组氨酸-苯丙氨酰基-氨酰-甘氨酰-脯氨酸和牛脑多肽等药物，注意到后者药物显示出最大的有效性作为在产妇剥夺条件下补偿对慢性应激的反应的手段。
