Abstract：
OBJECTIVE: To investigate the associations of body mass index (BMI), waist circumference (WC) and the weight-adjusted waist index (WWI) with the impairment of activities of daily living (ADL) in older Chinese people.
METHODS: A total of 13 260 participants aged 65 years and older from the 2018 Chinese Longitudinal Healthy Longevity Survey were included in this cross-sectional study. BMI, WC and the WWI were calculated from measurements of height, weight and WC. Binary logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs). Non-linear correlations were investigated using restricted cubic spline curves.
RESULTS: In multivariate logistic regression fully adjusted for confounding variables, our analyses revealed significant associations between WC and WWI and ADL impairment, with adjusted ORs (95% CI) of 1.01 (1.00, 1.01) and 1.08 (1.03, 1.12), respectively. Meanwhile, participants with a high WWI had a higher risk of ADL impairment compared with those with a low WWI, with an adjusted OR (95% CI) of 1.12 (1.02, 1.23). Subgroup analyses showed that only the association between WWI and ADL impairment did not differ in any of the different populations. In addition, we found that BMI, WC and WWI were non-linearly associated with ADL impairment.
CONCLUSIONS: There are significant associations between WC and WWI and ADL impairment in older Chinese people. The findings show the ability of the WWI to serve as a comprehensive and effective indicator of obesity in older Chinese people and emphasize the importance of assessing WWI in screening and preventing ADL impairment in older people.
METHODS: A total of 13 260 participants aged 65 years and older from the 2018 Chinese Longitudinal Healthy Longevity Survey were included in this cross-sectional study. BMI, WC and the WWI were calculated from measurements of height, weight and WC. Binary logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs). Non-linear correlations were investigated using restricted cubic spline curves.
RESULTS: In multivariate logistic regression fully adjusted for confounding variables, our analyses revealed significant associations between WC and WWI and ADL impairment, with adjusted ORs (95% CI) of 1.01 (1.00, 1.01) and 1.08 (1.03, 1.12), respectively. Meanwhile, participants with a high WWI had a higher risk of ADL impairment compared with those with a low WWI, with an adjusted OR (95% CI) of 1.12 (1.02, 1.23). Subgroup analyses showed that only the association between WWI and ADL impairment did not differ in any of the different populations. In addition, we found that BMI, WC and WWI were non-linearly associated with ADL impairment.
CONCLUSIONS: There are significant associations between WC and WWI and ADL impairment in older Chinese people. The findings show the ability of the WWI to serve as a comprehensive and effective indicator of obesity in older Chinese people and emphasize the importance of assessing WWI in screening and preventing ADL impairment in older people.
摘要：
目的：探讨身体质量指数(BMI)、腰围（WC）和体重调整后的腰围指数（WWI）与中国老年人日常生活活动能力（ADL）的损害。
方法：这项横断面研究共纳入了2018年中国纵向健康长寿调查的13260名65岁及以上的参与者。BMI,WC和WWI是根据身高测量值计算的，重量和WC。二元逻辑回归用于估计比值比（OR）和95％置信区间（95％CIs）。使用受限三次样条曲线研究了非线性相关性。
结果：在对混杂变量进行完全调整的多元逻辑回归中，我们的分析揭示了WC与WWI和ADL损害之间的显著关联，调整后的OR（95%CI）为1.01（1.00，1.01）和1.08（1.03，1.12），分别。同时,与WWI低的参与者相比，WWI高的参与者ADL受损的风险更高，调整后的OR（95%CI）为1.12（1.02，1.23）。亚组分析表明，在任何不同人群中，只有WWI和ADL受损之间的关联没有差异。此外,我们发现BMI,WC和WWI与ADL损害呈非线性相关。
结论：在中国老年人中，WC与WWI和ADL损害之间存在显著关联。研究结果表明，WWI能够作为中国老年人肥胖的全面有效指标，并强调了评估WWI在筛查和预防老年人ADL损害中的重要性。
方法：这项横断面研究共纳入了2018年中国纵向健康长寿调查的13260名65岁及以上的参与者。BMI,WC和WWI是根据身高测量值计算的，重量和WC。二元逻辑回归用于估计比值比（OR）和95％置信区间（95％CIs）。使用受限三次样条曲线研究了非线性相关性。
结果：在对混杂变量进行完全调整的多元逻辑回归中，我们的分析揭示了WC与WWI和ADL损害之间的显著关联，调整后的OR（95%CI）为1.01（1.00，1.01）和1.08（1.03，1.12），分别。同时,与WWI低的参与者相比，WWI高的参与者ADL受损的风险更高，调整后的OR（95%CI）为1.12（1.02，1.23）。亚组分析表明，在任何不同人群中，只有WWI和ADL受损之间的关联没有差异。此外,我们发现BMI,WC和WWI与ADL损害呈非线性相关。
结论：在中国老年人中，WC与WWI和ADL损害之间存在显著关联。研究结果表明，WWI能够作为中国老年人肥胖的全面有效指标，并强调了评估WWI在筛查和预防老年人ADL损害中的重要性。
