关键词: air embolism cerebral embolism cerebral stroke hyperbaric oxygen therapy neurological emergency

来  源:   DOI:10.3389/fneur.2024.1417006   PDF(Pubmed)

Abstract:
UNASSIGNED: Cerebral air embolism (CAE) is an uncommon medical emergency with a potentially fatal course. We have retrospectively analyzed a set of patients treated with CAE at our comprehensive stroke center and a hyperbaric medicine center. An overview of the pathophysiology, causes, diagnosis, and treatment of CAE is provided.
UNASSIGNED: We retrospectively identified 11 patients with cerebral venous and arterial air emboli that highlight the diversity in etiologies, manifestations, and disease courses encountered clinically. Acute-onset stroke syndrome and a progressive impairment of consciousness were the two most common presentations in four patients each (36%). Two patients (18%) suffered from an acute-onset coma, and one (9%) was asymptomatic. Four patients (36%) were treated with hyperbaric oxygen therapy (HBTO), high-flow oxygen therapy without HBOT was started in two patients (18%), two patients (18%) were in critical care at the time of diagnosis and three (27%) received no additional treatment. CAE was fatal in five cases (46%), caused severe disability in two (18%), mild disability in three (27%), and a single patient had no lasting deficit (9%).
UNASSIGNED: Cerebral air embolism is a dangerous condition that necessitates high clinical vigilance. Due to its diverse presentation, the diagnosis can be missed or delayed in critically ill patients and result in long-lasting or fatal neurological complications. Preventative measures and a proper diagnostic and treatment approach reduce CAE\'s incidence and impact.
摘要:
脑空气栓塞(CAE)是一种罕见的医疗紧急情况,具有潜在的致命病程。我们回顾性分析了在我们的综合卒中中心和高压医学中心接受CAE治疗的一组患者。病理生理学概述,原因,诊断,并提供CAE的治疗。
我们回顾性地确定了11例脑静脉和动脉空气栓塞患者,这些患者突出了病因的多样性。表现,和临床上遇到的疾病课程。急性发作性中风综合征和进行性意识障碍是四名患者中最常见的两种表现(36%)。两名患者(18%)患有急性昏迷,1人(9%)无症状。4例患者(36%)接受高压氧治疗(HBTO),两名患者(18%)开始了无HBOT的高流量氧疗,2例(18%)在确诊时接受重症监护,3例(27%)未接受额外治疗.CAE死亡5例(46%),造成严重残疾的两个(18%),三人轻度残疾(27%),1例患者无持续性缺陷(9%).
脑空气栓塞是一种危险的情况,需要高度的临床警惕。由于其多样化的表现,危重病人可能漏诊或延误诊断,并导致长期或致命的神经系统并发症.预防措施和适当的诊断和治疗方法可降低CAE的发生率和影响。
公众号