PDF(Pubmed)
Abstract：
UNASSIGNED: Trazodone is an antidepressant agent approved for treating major depressive disorders and is also prescribed for insomnia due to its sedative effect. In a few cases, trazodone was associated with parkinsonism. Herein, we describe a case of parkinsonism after a brief exposure to a moderate dose of trazodone.
UNASSIGNED: To describe a case of a patient with trazodone-induced parkinsonism in which the diagnosis was suspected after the exclusion of other common and serious causes.
UNASSIGNED: A case report of trazodone-induced parkinsonism.
UNASSIGNED: A 58-year-old male with sleeping problems was prescribed trazodone 50 mg daily at bedtime. The subject doubled the dosage without medical advice a week later. After 14 days of trazodone treatment, he started to experience difficulty in moving his upper limbs and recurrent falling. Neuroimaging, electrodiagnostic studies, and laboratory exams were unremarkable. Trazodone was discontinued, and the patient fully recovered. Noteworthy, the patient developed a recurrence of the motor symptoms with trazodone-rechallenge.
UNASSIGNED: Our case showed reversibly induced parkinsonism after a short intake of a moderate dose of trazodone which was prescribed for insomnia. The patient had a complete recovery after trazodone withdrawal. Noteworthy, the symptoms recurred upon trazodone-rechallenge.
UNASSIGNED: To describe a case of a patient with trazodone-induced parkinsonism in which the diagnosis was suspected after the exclusion of other common and serious causes.
UNASSIGNED: A case report of trazodone-induced parkinsonism.
UNASSIGNED: A 58-year-old male with sleeping problems was prescribed trazodone 50 mg daily at bedtime. The subject doubled the dosage without medical advice a week later. After 14 days of trazodone treatment, he started to experience difficulty in moving his upper limbs and recurrent falling. Neuroimaging, electrodiagnostic studies, and laboratory exams were unremarkable. Trazodone was discontinued, and the patient fully recovered. Noteworthy, the patient developed a recurrence of the motor symptoms with trazodone-rechallenge.
UNASSIGNED: Our case showed reversibly induced parkinsonism after a short intake of a moderate dose of trazodone which was prescribed for insomnia. The patient had a complete recovery after trazodone withdrawal. Noteworthy, the symptoms recurred upon trazodone-rechallenge.
摘要：
■曲唑酮是一种被批准用于治疗重度抑郁症的抗抑郁药，并且由于其镇静作用也被用于治疗失眠。在少数情况下,曲唑酮与帕金森病有关。在这里，我们描述了短暂暴露于中等剂量曲唑酮后的帕金森病病例。
■描述一例曲唑酮诱发的帕金森病患者，在排除其他常见和严重原因后怀疑诊断。
■曲唑酮致帕金森病1例报告.
■一名有睡眠问题的58岁男性在睡前每天服用50毫克曲唑酮。一周后，受试者在没有医疗建议的情况下将剂量加倍。曲唑酮治疗14天后，他开始感到上肢活动困难和反复跌倒。神经影像学,电诊断研究，实验室考试并不引人注目。曲唑酮停产了,病人完全康复了.值得注意的是,曲唑酮再激发后,患者出现运动症状复发.
■我们的病例显示，在短期摄入治疗失眠的中等剂量曲唑酮后，可逆转诱发帕金森病。曲唑酮停药后，患者完全康复。值得注意的是,再次使用曲唑酮后症状复发.
■描述一例曲唑酮诱发的帕金森病患者，在排除其他常见和严重原因后怀疑诊断。
■曲唑酮致帕金森病1例报告.
■一名有睡眠问题的58岁男性在睡前每天服用50毫克曲唑酮。一周后，受试者在没有医疗建议的情况下将剂量加倍。曲唑酮治疗14天后，他开始感到上肢活动困难和反复跌倒。神经影像学,电诊断研究，实验室考试并不引人注目。曲唑酮停产了,病人完全康复了.值得注意的是,曲唑酮再激发后,患者出现运动症状复发.
■我们的病例显示，在短期摄入治疗失眠的中等剂量曲唑酮后，可逆转诱发帕金森病。曲唑酮停药后，患者完全康复。值得注意的是,再次使用曲唑酮后症状复发.
