PDF(Pubmed)
Abstract：
OBJECTIVE: Shift work and Shift Work Sleep Disorder (SWSD) are known to affect the secretion of several neurotransmitters and hormones associated with premature ejaculation (PE). However, their specific influence on the regulation of male ejaculation remains unclear. This study explores the relationship between shift work, SWSD, and PE.
METHODS: From April to October 2023, a cross-sectional survey was conducted across five regions of China to explore the work schedules, sleep quality, and sexual function of male workers. Participants\' sleep quality was evaluated using a validated SWSD questionnaire, and their erectile function and ejaculatory control were assessed with the International Inventory of Erectile Function (IIEF-5) scores and Premature Ejaculation Diagnostic Tool (PEDT) scores, respectively. Univariate and multivariate linear regression analyses were employed to identify risk factors associated with PE. Confounders were controlled using multiple regression models, and clinical prediction models were developed to predict PE onset and assess the contribution of risk factors.
RESULTS: The study included 1239 eligible participants, comprising 840 non-shift workers and 399 shift workers (148 with SWSD and 251 without SWSD). Compared to non-shift working males, those involved in shift work (β 1.58, 95% CI 0.75 - 2.42, p < 0.001) and those suffering from SWSD (β 2.86, 95% CI 1.86 - 3.85, p < 0.001) they had significantly higher PEDT scores. Additionally, we identified daily sleep of less than six hours, depression, anxiety, diabetes, hyperlipidemia, frequent alcohol consumption (more than twice a week), and erectile dysfunction as risk factors for PE. The predictive model for PE demonstrated commendable efficacy.
CONCLUSIONS: Both shift work and SWSD significantly increase the risk of premature ejaculation, with the risk magnifying in tandem with the duration of shift work. This study reveals the potential impact of shift work and SWSD on PE and provides new theoretical foundations for the risk assessment and prevention of this condition.
METHODS: From April to October 2023, a cross-sectional survey was conducted across five regions of China to explore the work schedules, sleep quality, and sexual function of male workers. Participants\' sleep quality was evaluated using a validated SWSD questionnaire, and their erectile function and ejaculatory control were assessed with the International Inventory of Erectile Function (IIEF-5) scores and Premature Ejaculation Diagnostic Tool (PEDT) scores, respectively. Univariate and multivariate linear regression analyses were employed to identify risk factors associated with PE. Confounders were controlled using multiple regression models, and clinical prediction models were developed to predict PE onset and assess the contribution of risk factors.
RESULTS: The study included 1239 eligible participants, comprising 840 non-shift workers and 399 shift workers (148 with SWSD and 251 without SWSD). Compared to non-shift working males, those involved in shift work (β 1.58, 95% CI 0.75 - 2.42, p < 0.001) and those suffering from SWSD (β 2.86, 95% CI 1.86 - 3.85, p < 0.001) they had significantly higher PEDT scores. Additionally, we identified daily sleep of less than six hours, depression, anxiety, diabetes, hyperlipidemia, frequent alcohol consumption (more than twice a week), and erectile dysfunction as risk factors for PE. The predictive model for PE demonstrated commendable efficacy.
CONCLUSIONS: Both shift work and SWSD significantly increase the risk of premature ejaculation, with the risk magnifying in tandem with the duration of shift work. This study reveals the potential impact of shift work and SWSD on PE and provides new theoretical foundations for the risk assessment and prevention of this condition.
摘要：
目的：已知轮班工作和轮班工作睡眠障碍（SWSD）会影响与早泄（PE）相关的几种神经递质和激素的分泌。然而,它们对男性射精调节的具体影响尚不清楚。本研究探讨了轮班工作之间的关系，SWSD,和PE。
方法：从2023年4月至10月，在中国五个地区进行了横断面调查，以探索工作时间表，睡眠质量,和男性工人的性功能。使用经过验证的SWSD问卷评估参与者的睡眠质量，用国际勃起功能量表（IIEF-5）评分和早泄诊断工具（PEDT）评分评估其勃起功能和射精控制，分别。采用单变量和多元线性回归分析来确定与PE相关的危险因素。使用多元回归模型控制混杂因素，并建立了临床预测模型来预测PE发病和评估危险因素的贡献。
结果：该研究包括1239名符合条件的参与者，包括840名非轮班工人和399名轮班工人(148名具有SWSD，251名没有SWSD)。与不轮班工作的男性相比，那些参与轮班工作的人(β1.58,95%CI0.75-2.42,p<0.001)和那些患有SWSD的人(β2.86,95%CI1.86-3.85,p<0.001),他们的PEDT评分明显较高。此外,我们确定每天的睡眠少于6小时，抑郁症,焦虑,糖尿病,高脂血症,经常饮酒（每周两次以上），勃起功能障碍是PE的危险因素。PE的预测模型显示出值得称道的功效。
结论：轮班工作和SWSD均显着增加早泄的风险，风险随着轮班工作的持续时间而放大。本研究揭示了轮班工作和SWSD对PE的潜在影响，为这种情况的风险评估和预防提供了新的理论基础。
方法：从2023年4月至10月，在中国五个地区进行了横断面调查，以探索工作时间表，睡眠质量,和男性工人的性功能。使用经过验证的SWSD问卷评估参与者的睡眠质量，用国际勃起功能量表（IIEF-5）评分和早泄诊断工具（PEDT）评分评估其勃起功能和射精控制，分别。采用单变量和多元线性回归分析来确定与PE相关的危险因素。使用多元回归模型控制混杂因素，并建立了临床预测模型来预测PE发病和评估危险因素的贡献。
结果：该研究包括1239名符合条件的参与者，包括840名非轮班工人和399名轮班工人(148名具有SWSD，251名没有SWSD)。与不轮班工作的男性相比，那些参与轮班工作的人(β1.58,95%CI0.75-2.42,p<0.001)和那些患有SWSD的人(β2.86,95%CI1.86-3.85,p<0.001),他们的PEDT评分明显较高。此外,我们确定每天的睡眠少于6小时，抑郁症,焦虑,糖尿病,高脂血症,经常饮酒（每周两次以上），勃起功能障碍是PE的危险因素。PE的预测模型显示出值得称道的功效。
结论：轮班工作和SWSD均显着增加早泄的风险，风险随着轮班工作的持续时间而放大。本研究揭示了轮班工作和SWSD对PE的潜在影响，为这种情况的风险评估和预防提供了新的理论基础。
