PDF(Pubmed)
Abstract：
UNASSIGNED: To determine the angiographic severity of coronary artery disease (CAD) and assess the influence of major cardiovascular risk factors (CVRF).
UNASSIGNED: a cross-sectional, hospital-based study.
UNASSIGNED: the catheterisation laboratory of the National Cardiothoracic Centre, Accra, Ghana.
UNASSIGNED: for 12 months, consecutive patients admitted for coronary angiography were assessed for the presence of CVRFs. Those with significant CAD after angiography were recruited into the study.
UNASSIGNED: The patient\'s angiograms were analysed, and the CAD severity was obtained using the SYNTAX scoring criteria.
UNASSIGNED: The lesion overall severity (SYNTAX) score and the relationship with CVRFs present.
UNASSIGNED: out of the 169 patients that had coronary angiography, 78 had significant CAD. The mean SYNTAX score was 20.18 (SD= 10.68), with a significantly higher value in dyslipidaemic patients (p < 0.001). Pearson\'s correlation between the score and BMI was weak (r= 0.256, p= 0.034). The occurrence of high SYNTAX score lesions in about 18% of the population was significantly associated with hypertension (OR= 1.304, 95% CI [1.13-1.50]; p= 0.017) dyslipidaemia (OR= 5.636, 95% CI [1.17-27.23]; p= 0.019), and obesity (OR= 3.960, 95% CI [1.18-13.34]; p= 0.021). However, after adjusting for confounding factors, only dyslipidaemia significantly influenced its occurrence (aOR= 5.256, 95% CI [1.03-26.96]; p= 0.047).
UNASSIGNED: Even though the most severe form of CAD was found in about one-fifth of the study population, its occurrence was strongly influenced by the presence of dyslipidaemia.
UNASSIGNED: None.
UNASSIGNED: a cross-sectional, hospital-based study.
UNASSIGNED: the catheterisation laboratory of the National Cardiothoracic Centre, Accra, Ghana.
UNASSIGNED: for 12 months, consecutive patients admitted for coronary angiography were assessed for the presence of CVRFs. Those with significant CAD after angiography were recruited into the study.
UNASSIGNED: The patient\'s angiograms were analysed, and the CAD severity was obtained using the SYNTAX scoring criteria.
UNASSIGNED: The lesion overall severity (SYNTAX) score and the relationship with CVRFs present.
UNASSIGNED: out of the 169 patients that had coronary angiography, 78 had significant CAD. The mean SYNTAX score was 20.18 (SD= 10.68), with a significantly higher value in dyslipidaemic patients (p < 0.001). Pearson\'s correlation between the score and BMI was weak (r= 0.256, p= 0.034). The occurrence of high SYNTAX score lesions in about 18% of the population was significantly associated with hypertension (OR= 1.304, 95% CI [1.13-1.50]; p= 0.017) dyslipidaemia (OR= 5.636, 95% CI [1.17-27.23]; p= 0.019), and obesity (OR= 3.960, 95% CI [1.18-13.34]; p= 0.021). However, after adjusting for confounding factors, only dyslipidaemia significantly influenced its occurrence (aOR= 5.256, 95% CI [1.03-26.96]; p= 0.047).
UNASSIGNED: Even though the most severe form of CAD was found in about one-fifth of the study population, its occurrence was strongly influenced by the presence of dyslipidaemia.
UNASSIGNED: None.
摘要：
■确定冠状动脉疾病（CAD）的血管造影严重程度并评估主要心血管危险因素（CVRF）的影响。
■横截面，以医院为基础的研究。
■国家心胸中心的导管插入实验室，阿克拉,加纳。
■12个月，对连续入院行冠状动脉造影的患者进行CVRFs的评估.血管造影后有明显CAD的患者被纳入研究。
■分析了患者的血管造影照片，使用SYNTAX评分标准获得CAD严重程度。
■病变总体严重程度（SYNTAX）评分以及与CVRF存在的关系。
■在169例冠状动脉造影患者中，78有显著的CAD。SYNTAX平均得分为20.18（SD=10.68），在血脂异常患者中具有明显更高的价值（p<0.001）。Pearson评分与BMI的相关性较弱(r=0.256,p=0.034)。约18%的人群发生高SYNTAX评分病变与高血压(OR=1.304,95%CI[1.13-1.50];p=0.017)血脂异常(OR=5.636,95%CI[1.17-27.23];p=0.019)显著相关,和肥胖(OR=3.960，95%CI[1.18-13.34]；p=0.021)。然而,在对混杂因素进行调整后，只有血脂异常显著影响其发生(aOR=5.256,95%CI[1.03-26.96];p=0.047)。
■尽管在约五分之一的研究人群中发现了最严重的CAD形式，其发生受到血脂异常的强烈影响.
■无。
■横截面，以医院为基础的研究。
■国家心胸中心的导管插入实验室，阿克拉,加纳。
■12个月，对连续入院行冠状动脉造影的患者进行CVRFs的评估.血管造影后有明显CAD的患者被纳入研究。
■分析了患者的血管造影照片，使用SYNTAX评分标准获得CAD严重程度。
■病变总体严重程度（SYNTAX）评分以及与CVRF存在的关系。
■在169例冠状动脉造影患者中，78有显著的CAD。SYNTAX平均得分为20.18（SD=10.68），在血脂异常患者中具有明显更高的价值（p<0.001）。Pearson评分与BMI的相关性较弱(r=0.256,p=0.034)。约18%的人群发生高SYNTAX评分病变与高血压(OR=1.304,95%CI[1.13-1.50];p=0.017)血脂异常(OR=5.636,95%CI[1.17-27.23];p=0.019)显著相关,和肥胖(OR=3.960，95%CI[1.18-13.34]；p=0.021)。然而,在对混杂因素进行调整后，只有血脂异常显著影响其发生(aOR=5.256,95%CI[1.03-26.96];p=0.047)。
■尽管在约五分之一的研究人群中发现了最严重的CAD形式，其发生受到血脂异常的强烈影响.
■无。
