关键词: Conservative therapy pathophysiology postoperative care spinal infection spondylodiscitis surgical intervention

来  源:   DOI:10.4103/jcvjs.jcvjs_164_23   PDF(Pubmed)

Abstract:
UNASSIGNED: Spondylodiscitis (SD) is an inflammatory condition affecting the intervertebral discs and adjacent structures, often leading to serious complications, including epidural abscesses. This study aimed to differentiate postoperative SD from spontaneous cases caused by osteoporotic defects and associated pathologies, evaluating the frequency of SD in spinal diseases at a single center.
UNASSIGNED: A retrospective observational study involving 25 patients was conducted, analyzing variations between postoperative revisions in SD patients and spontaneous SD due to concurrent pathology and osteoporotic defects. The effects of postoperative wound healing following transforaminal lumbar interbody fusion and decompressive hemilaminectomy with pedicle screws were also investigated. Ethical guidelines were strictly followed during the study, conducted from January 2023 to September 2023 at Moscow City Clinical Hospital No. 68, Demikhova V.P.
UNASSIGNED: Among the 25 patients with spontaneous SD, 15 females and 10 males were included, with only two undergoing surgical revision. Predominant purulent inflammatory foci were observed at specific spinal levels, and demographics revealed prevalent comorbidities such as arterial hypertension (80%) and type 2 diabetes mellitus (60%). Postoperative complications included paravertebral abscesses and wound-related issues. Structural observations indicated vertebral destruction, joint gaps, and localized spinal canal narrowing, revealing complexities in SD cases.
UNASSIGNED: Surgical intervention remains crucial for addressing SD-related vertebral complications, while antimicrobial therapy tailored to specific pathogens is pivotal. Concurrent conditions necessitate comprehensive management, often involving cardiological interventions. Postoperatively, a combined approach of conservative therapy and calcium phosphate adjuncts is recommended, especially considering the observed low bone density, aiming to optimize patient recovery and spinal stability.
摘要:
脊椎盘炎(SD)是一种影响椎间盘和相邻结构的炎症性疾病,经常导致严重的并发症,包括硬膜外脓肿。这项研究旨在区分术后SD与由骨质疏松性缺损和相关病理导致的自发性病例。在单个中心评估脊髓疾病中SD的频率。
进行了一项涉及25名患者的回顾性观察研究,分析SD患者术后翻修与并发病理和骨质疏松性缺损引起的自发性SD之间的差异。还研究了经椎间孔腰椎椎间融合术和椎弓根螺钉减压半椎板切除术后伤口愈合的效果。在研究过程中严格遵守道德准则,于2023年1月至2023年9月在莫斯科市临床医院进行。68,DemikhovaV.P.
在25例自发性SD患者中,包括15名女性和10名男性,只有两个人在做手术.在特定的脊髓水平观察到主要的化脓性炎症灶,人口统计学显示普遍存在合并症,例如动脉高血压(80%)和2型糖尿病(60%)。术后并发症包括椎旁脓肿和伤口相关问题。结构观察显示椎体破坏,接头间隙,局部椎管狭窄,揭示SD病例的复杂性。
手术干预对于解决SD相关的椎体并发症仍然至关重要,而针对特定病原体的抗菌治疗至关重要。并发条件需要全面管理,通常涉及心脏干预。术后,建议采用保守治疗和磷酸钙辅助治疗的联合方法,特别是考虑到观察到的低骨密度,旨在优化患者康复和脊柱稳定性。
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