PDF(Pubmed)
Abstract：
UNASSIGNED: The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.
UNASSIGNED: Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.
UNASSIGNED: Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, Ghana.
UNASSIGNED: All adult patients with histologically diagnosed lung cancer were enrolled.
UNASSIGNED: Lung cancer histological types.
UNASSIGNED: The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the predominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.
UNASSIGNED: The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.
UNASSIGNED: None declared.
UNASSIGNED: Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.
UNASSIGNED: Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, Ghana.
UNASSIGNED: All adult patients with histologically diagnosed lung cancer were enrolled.
UNASSIGNED: Lung cancer histological types.
UNASSIGNED: The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the predominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.
UNASSIGNED: The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.
UNASSIGNED: None declared.
摘要：
■该研究试图确定三级机构中一组肺癌患者的临床特征和组织学亚型。
■回顾性回顾3年期间在呼吸道诊所的组织学确诊肺癌病例的医疗记录。
■呼吸诊所，Korle-Bu教学医院,阿克拉,加纳。
■纳入所有经组织学诊断为肺癌的成年患者。
■肺癌组织学类型。
■肺癌病例比例为12.4%。大多数为女性（57.8％），诊断时的平均年龄为55.8±16.0岁。患者主要是非吸烟者（61%）。常见症状为慢性咳嗽和胸痛。超过三分之二的病例出现在临床III和IV期，主要的组织学亚型是吸烟者和非吸烟者的腺癌。对表皮生长因子受体（EGFR）和间变性淋巴瘤激酶（ALK）突变的基因检测基本上不存在。
■大多数肺癌患者晚期疾病。腺癌是主要的非吸烟人群的主要组织学亚型，在不到60岁的女性中患病率增加。这应该鼓励检测基因突变，以提高患者的生存率。
■没有声明。
■回顾性回顾3年期间在呼吸道诊所的组织学确诊肺癌病例的医疗记录。
■呼吸诊所，Korle-Bu教学医院,阿克拉,加纳。
■纳入所有经组织学诊断为肺癌的成年患者。
■肺癌组织学类型。
■肺癌病例比例为12.4%。大多数为女性（57.8％），诊断时的平均年龄为55.8±16.0岁。患者主要是非吸烟者（61%）。常见症状为慢性咳嗽和胸痛。超过三分之二的病例出现在临床III和IV期，主要的组织学亚型是吸烟者和非吸烟者的腺癌。对表皮生长因子受体（EGFR）和间变性淋巴瘤激酶（ALK）突变的基因检测基本上不存在。
■大多数肺癌患者晚期疾病。腺癌是主要的非吸烟人群的主要组织学亚型，在不到60岁的女性中患病率增加。这应该鼓励检测基因突变，以提高患者的生存率。
■没有声明。
