%0 Journal Article
%T A three-year review of lung cancer patient characteristics in a tertiary hospital.
%A Afriyie-Mensah JS
%A Kwarteng E
%A Tetteh J
%A Gbadamosi H
%A Dadzie MA
%A Mensah YB
%A Entsua-Mensah E
%J Ghana Med J
%V 57
%N 3
%D 2023 Sep
%M 38957673
暂无%R 10.4314/gmj.v57i3.2
%X <B>UNASSIGNED: </B>The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.<BR><B>UNASSIGNED: </B>Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.<BR><B>UNASSIGNED: </B>Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, Ghana.<BR><B>UNASSIGNED: </B>All adult patients with histologically diagnosed lung cancer were enrolled.<BR><B>UNASSIGNED: </B>Lung cancer histological types.<BR><B>UNASSIGNED: </B>The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the predominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.<BR><B>UNASSIGNED: </B>The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.<BR><B>UNASSIGNED: </B>None declared.