PDF(Pubmed)
Abstract：
UNASSIGNED: The study aimed to detect the presence of Helicobacter pylori infection in children using two investigative methods: the rapid urease test and histological methods. It also examined the relationship between socioeconomic status and Helicobacter pylori infection.
UNASSIGNED: This was a cross-sectional study conducted in the paediatric theatre at Korle Bu Teaching Hospital in Accra, Ghana.
UNASSIGNED: Children who were scheduled for upper gastrointestinal endoscopy were recruited into the study.
UNASSIGNED: The presence of Helicobacter pylori in gastric biopsies was measured using a rapid urease test and histology.
UNASSIGNED: Seventy-three children aged 2 years to 16 years were seen during the period. Both tests were positive at the same time in 36 (49.3%) out of the 73 children (p<0.0001). The positivity rates for the rapid urease test and histology were 57.5% and 53.4 %, respectively. Significant predictors of the histology presence of H. pylori were a large household size of at least 6 members (AOR: 4.03; p<0.013) and the presence of pets at home (AOR: 3.23; p<0.044).
UNASSIGNED: Substantial agreement was found between the rapid urease test and histology examination of gastric biopsies for the presence of H. pylori. Children from large households and those with pets at home appear to have increased odds of having H. pylori infection of the gastric mucosa.
UNASSIGNED: None declared.
UNASSIGNED: This was a cross-sectional study conducted in the paediatric theatre at Korle Bu Teaching Hospital in Accra, Ghana.
UNASSIGNED: Children who were scheduled for upper gastrointestinal endoscopy were recruited into the study.
UNASSIGNED: The presence of Helicobacter pylori in gastric biopsies was measured using a rapid urease test and histology.
UNASSIGNED: Seventy-three children aged 2 years to 16 years were seen during the period. Both tests were positive at the same time in 36 (49.3%) out of the 73 children (p<0.0001). The positivity rates for the rapid urease test and histology were 57.5% and 53.4 %, respectively. Significant predictors of the histology presence of H. pylori were a large household size of at least 6 members (AOR: 4.03; p<0.013) and the presence of pets at home (AOR: 3.23; p<0.044).
UNASSIGNED: Substantial agreement was found between the rapid urease test and histology examination of gastric biopsies for the presence of H. pylori. Children from large households and those with pets at home appear to have increased odds of having H. pylori infection of the gastric mucosa.
UNASSIGNED: None declared.
摘要：
■该研究旨在使用两种研究方法来检测儿童中幽门螺杆菌感染的存在：快速尿素酶测试和组织学方法。它还研究了社会经济地位与幽门螺杆菌感染之间的关系。
这是一项在阿克拉KorleBu教学医院儿科剧院进行的横断面研究，加纳。
■计划进行上消化道内镜检查的儿童被纳入研究。
■胃活检中幽门螺杆菌的存在使用快速尿素酶试验和组织学检测。
■在此期间发现了73名2岁至16岁的儿童。在73名儿童中，有36名（49.3％）的两项测试同时呈阳性（p<0.0001）。快速脲酶试验和组织学阳性率分别为57.5%和53.4%,分别。幽门螺杆菌组织学存在的重要预测因素是至少6个成员的大型家庭(AOR:4.03;p<0.013)和家中存在宠物(AOR:3.23;p<0.044)。
■对于幽门螺杆菌的存在，在快速尿素酶试验和胃活组织检查之间发现了实质的一致性。来自大型家庭的儿童和在家中有宠物的儿童似乎增加了胃粘膜感染幽门螺杆菌的几率。
■没有声明。
这是一项在阿克拉KorleBu教学医院儿科剧院进行的横断面研究，加纳。
■计划进行上消化道内镜检查的儿童被纳入研究。
■胃活检中幽门螺杆菌的存在使用快速尿素酶试验和组织学检测。
■在此期间发现了73名2岁至16岁的儿童。在73名儿童中，有36名（49.3％）的两项测试同时呈阳性（p<0.0001）。快速脲酶试验和组织学阳性率分别为57.5%和53.4%,分别。幽门螺杆菌组织学存在的重要预测因素是至少6个成员的大型家庭(AOR:4.03;p<0.013)和家中存在宠物(AOR:3.23;p<0.044)。
■对于幽门螺杆菌的存在，在快速尿素酶试验和胃活组织检查之间发现了实质的一致性。来自大型家庭的儿童和在家中有宠物的儿童似乎增加了胃粘膜感染幽门螺杆菌的几率。
■没有声明。
