关键词: COVID-19 age-standardized mortality rate excess mortality female tuberculosis

Mesh : Humans COVID-19 / mortality Female Middle Aged Male United States / epidemiology Adult Aged Tuberculosis / mortality Sex Factors Aged, 80 and over Pandemics

来  源:   DOI:10.3389/fpubh.2024.1413604   PDF(Pubmed)

Abstract:
UNASSIGNED: We aimed to determine the trend of TB-related deaths during the COVID-19 pandemic.
UNASSIGNED: TB-related mortality data of decedents aged ≥25 years from 2006 to 2021 were analyzed. Excess deaths were estimated by determining the difference between observed and projected mortality rates during the pandemic.
UNASSIGNED: A total of 18,628 TB-related deaths were documented from 2006 to 2021. TB-related age-standardized mortality rates (ASMRs) were 0.51 in 2020 and 0.52 in 2021, corresponding to an excess mortality of 10.22 and 9.19%, respectively. Female patients with TB demonstrated a higher relative increase in mortality (26.33 vs. 2.17% in 2020; 21.48 vs. 3.23% in 2021) when compared to male. Female aged 45-64 years old showed a surge in mortality, with an annual percent change (APC) of -2.2% pre-pandemic to 22.8% (95% CI: -1.7 to 68.7%) during the pandemic, corresponding to excess mortalities of 62.165 and 99.16% in 2020 and 2021, respectively; these excess mortality rates were higher than those observed in the overall female population ages 45-64 years in 2020 (17.53%) and 2021 (33.79%).
UNASSIGNED: The steady decline in TB-related mortality in the United States has been reversed by COVID-19. Female with TB were disproportionately affected by the pandemic.
摘要:
我们的目的是确定COVID-19大流行期间与结核病相关的死亡趋势。
分析了2006年至2021年年龄≥25岁的死者的结核病相关死亡率数据。通过确定大流行期间观察到的死亡率和预测的死亡率之间的差异来估计过量死亡。
从2006年到2021年,共记录了18,628例结核病相关死亡。与结核病相关的年龄标准化死亡率(ASMR)在2020年为0.51,在2021年为0.52,对应的超额死亡率为10.22和9.19%,分别。女性结核病患者的死亡率相对增加较高(26.33vs.2020年为2.17%;21.48与2021年为3.23%),与男性相比。45-64岁的女性死亡率上升,大流行前的年度百分比变化(APC)为-2.2%,大流行期间为22.8%(95%CI:-1.7至68.7%),对应于2020年和2021年分别为62.165和99.16%的超额死亡率;这些超额死亡率高于2020年(17.53%)和2021年(33.79%)的45-64岁女性总人口中观察到的死亡率.
美国结核病相关死亡率的稳步下降已被COVID-19逆转。患有结核病的女性受到大流行的影响尤其严重。
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