PDF(Pubmed)
Abstract：
BACKGROUND: Healthcare Workers (HCWs) are susceptible to hepatitis B virus (HBV) infection and are advised to receive vaccination. However, vaccination rates remain low in developing countries. There is little data concerning Hepatitis B (HepB) vaccination and information regarding HBV knowledge among HCWs in Cambodia. This study aimed to evaluate the knowledge of HBV infection, HepB vaccine, and vaccination status with its associated factors among HCWs in Cambodia.
METHODS: A Cross-sectional study was conducted among HCWs in Kampot and Kep Provinces, Cambodia, from September to October 2023 using a questionnaire survey. A total of 261 HCWs were recruited from 1,309 individuals working in all 83 health facilities using systematic random sampling methods. Statistical analyses including the χ2-test and multivariate logistic regression were conducted to identify factors associated with vaccination among the participants.
RESULTS: Among 259 participants, 62.9% showed good knowledge of HBV infection, and 65.6% demonstrated good knowledge of the HepB vaccine. 59.8% of the participants had received the HepB vaccine, while 40.2% remained unvaccinated. Analysis showed that HCWs working at Provincial Health Department/Operational Districts and Provincial Referral Hospital/Referral Hospitals were more likely to be vaccinated compared to those at Health Centers [AOR = 6.5; CI = 1.1-39.5, p = 0.0403; AOR = 2.8, CI = 1.0-7.8, p = 0.0412], respectively. Furthermore, individuals with good knowledge of the HBV infection and vaccine were more likely to receive the vaccine compared to those with inadequate knowledge [AOR = 6.3; CI = 3.3-12.3, p < .0001; AOR = 3.7, CI = 1.9-7.4, p = 0.0001], respectively. Within the unvaccinated HCWs, 32% reported high vaccine costs as a barrier, 33% mentioned workplace vaccine was not for adults, and 59% reported insufficient education on adult HepB vaccination.
CONCLUSIONS: The HepB vaccination coverage among HCWs is at 59.8%, which is below the World Health Organization\'s (WHO) recommendation rate of 100%. Knowledge of HBV infection and HepB vaccine were good predictive factors for vaccination. The high cost of vaccine, workplace vaccine not for adults, and insufficient education on adult vaccination were found as barriers to vaccination. This study underscores the importance of providing education to HCWs on HBV infection and the HepB vaccine. Furthermore, it highlights the need for a policy that ensures free vaccination for HCWs.
METHODS: A Cross-sectional study was conducted among HCWs in Kampot and Kep Provinces, Cambodia, from September to October 2023 using a questionnaire survey. A total of 261 HCWs were recruited from 1,309 individuals working in all 83 health facilities using systematic random sampling methods. Statistical analyses including the χ2-test and multivariate logistic regression were conducted to identify factors associated with vaccination among the participants.
RESULTS: Among 259 participants, 62.9% showed good knowledge of HBV infection, and 65.6% demonstrated good knowledge of the HepB vaccine. 59.8% of the participants had received the HepB vaccine, while 40.2% remained unvaccinated. Analysis showed that HCWs working at Provincial Health Department/Operational Districts and Provincial Referral Hospital/Referral Hospitals were more likely to be vaccinated compared to those at Health Centers [AOR = 6.5; CI = 1.1-39.5, p = 0.0403; AOR = 2.8, CI = 1.0-7.8, p = 0.0412], respectively. Furthermore, individuals with good knowledge of the HBV infection and vaccine were more likely to receive the vaccine compared to those with inadequate knowledge [AOR = 6.3; CI = 3.3-12.3, p < .0001; AOR = 3.7, CI = 1.9-7.4, p = 0.0001], respectively. Within the unvaccinated HCWs, 32% reported high vaccine costs as a barrier, 33% mentioned workplace vaccine was not for adults, and 59% reported insufficient education on adult HepB vaccination.
CONCLUSIONS: The HepB vaccination coverage among HCWs is at 59.8%, which is below the World Health Organization\'s (WHO) recommendation rate of 100%. Knowledge of HBV infection and HepB vaccine were good predictive factors for vaccination. The high cost of vaccine, workplace vaccine not for adults, and insufficient education on adult vaccination were found as barriers to vaccination. This study underscores the importance of providing education to HCWs on HBV infection and the HepB vaccine. Furthermore, it highlights the need for a policy that ensures free vaccination for HCWs.
摘要：
背景：医疗工作者（HCWs）对乙型肝炎病毒（HBV）感染易感，并建议接受疫苗接种。然而,发展中国家的疫苗接种率仍然很低。关于乙型肝炎（HepB）疫苗接种的数据很少，以及关于柬埔寨HCWs中HBV知识的信息。本研究旨在评估HBV感染的知识，HepB疫苗，柬埔寨HCWs的疫苗接种状况及其相关因素。
方法：在贡布省和Kep省的HCWs中进行了一项横断面研究，柬埔寨,2023年9月至10月使用问卷调查。使用系统随机抽样方法，从在所有83个医疗机构工作的1,309个人中招募了261名医务人员。进行了包括χ2检验和多变量逻辑回归的统计分析，以确定参与者中与疫苗接种相关的因素。
结果：在259名参与者中，62.9％表现出良好的HBV感染知识，65.6％的人对HepB疫苗有良好的了解。59.8％的参与者接受了HepB疫苗，而40.2%仍未接种疫苗。分析表明，与健康中心相比，在省卫生厅/行动区和省转诊医院/转诊医院工作的医护人员更有可能接种疫苗[AOR=6.5；CI=1.1-39.5，p=0.0403；AOR=2.8，CI=1.0-7.8，p=0.0412]，分别。此外，与知识不足的人相比，对HBV感染和疫苗有良好知识的人更有可能接种疫苗[AOR=6.3;CI=3.3-12.3，p<.0001;AOR=3.7，CI=1.9-7.4，p=0.0001]，分别。在未接种疫苗的HCWs中，32%的人报告说，高疫苗成本是一个障碍，33%提到的工作场所疫苗不是针对成年人的，59%的人报告对成人HepB疫苗接种的教育不足。
结论：HCWs中的HepB疫苗接种率为59.8％，低于世界卫生组织(WHO)100%的推荐率。了解HBV感染和HepB疫苗是疫苗接种的良好预测因素。疫苗的高成本，工作场所疫苗不适合成年人，成人疫苗接种教育不足被认为是疫苗接种的障碍。这项研究强调了对HBV感染和HepB疫苗提供教育的重要性。此外，它强调需要制定一项政策，确保为HCWs免费接种疫苗。
方法：在贡布省和Kep省的HCWs中进行了一项横断面研究，柬埔寨,2023年9月至10月使用问卷调查。使用系统随机抽样方法，从在所有83个医疗机构工作的1,309个人中招募了261名医务人员。进行了包括χ2检验和多变量逻辑回归的统计分析，以确定参与者中与疫苗接种相关的因素。
结果：在259名参与者中，62.9％表现出良好的HBV感染知识，65.6％的人对HepB疫苗有良好的了解。59.8％的参与者接受了HepB疫苗，而40.2%仍未接种疫苗。分析表明，与健康中心相比，在省卫生厅/行动区和省转诊医院/转诊医院工作的医护人员更有可能接种疫苗[AOR=6.5；CI=1.1-39.5，p=0.0403；AOR=2.8，CI=1.0-7.8，p=0.0412]，分别。此外，与知识不足的人相比，对HBV感染和疫苗有良好知识的人更有可能接种疫苗[AOR=6.3;CI=3.3-12.3，p<.0001;AOR=3.7，CI=1.9-7.4，p=0.0001]，分别。在未接种疫苗的HCWs中，32%的人报告说，高疫苗成本是一个障碍，33%提到的工作场所疫苗不是针对成年人的，59%的人报告对成人HepB疫苗接种的教育不足。
结论：HCWs中的HepB疫苗接种率为59.8％，低于世界卫生组织(WHO)100%的推荐率。了解HBV感染和HepB疫苗是疫苗接种的良好预测因素。疫苗的高成本，工作场所疫苗不适合成年人，成人疫苗接种教育不足被认为是疫苗接种的障碍。这项研究强调了对HBV感染和HepB疫苗提供教育的重要性。此外，它强调需要制定一项政策，确保为HCWs免费接种疫苗。
