关键词: Alternative matrices Forensic toxicology N-piperidinyl etonitazene NPS UHPLC-HRMS

Mesh : Humans Hair / chemistry Nails / chemistry Male Cadaver Forensic Toxicology Drug Overdose Benzimidazoles Analgesics, Opioid / analysis

来  源:   DOI:10.1016/j.jflm.2024.102710

Abstract:
This short report describes research on N-piperidinyl etonitazene, also known as etonitazepipne, in keratinous matrices (hair and nails) after death related to a suspected opioid overdose. Etonitazepipne belongs to the family of benzimidazole opioids, a class of new synthetic opioids that has penetrated the illicit drug market. Analysis in the case under study showed the presence of etonitazepipne in both hair and nails, confirming that the substance accumulates in the body with repeated intake.
摘要:
这篇简短的报告描述了对N-哌啶基依托氮嗪的研究,也被称为etonitazepne,在角质基质(头发和指甲)死亡后与怀疑阿片类药物过量有关。Etonitazepne属于苯并咪唑阿片类药物家族,一类新的合成阿片类药物,已经渗透到非法药物市场。在研究中的病例中的分析表明,头发和指甲中都存在etonitazepne,确认该物质在体内积累并反复摄入。
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