Abstract：
Resonance frequency analysis (RFA) is valuable for assessing implant status. In a previous investigation, acetabular cup fixation was assessed using laser RFA and the pull-down force was predicted in an in vitro setting. While the pull-down force alone is sufficient for initial fixation evaluation, it is desirable to evaluate the bone strength of the foundation for subsequent fixation. Diminished bone quality causes micromotion, migration, and protracted osseointegration, consequently elevating susceptibility to periprosthetic fractures and failure of ingrained trabecular bone. Limited research exists on the evaluation of bone mineral density (BMD) around the cup using RFA. For in vivo application of laser RFA, we implemented the sweep pulse excitation method and engineered an innovative laser RFA device having low laser energy and small dimensions. We focused on a specific frequency range (2500-4500 Hz), where the peak frequency was presumed to be influenced by foundational density. Quantitative computed tomography with a phantom was employed to assess periprosthetic BMD. Correlation between the resonance frequency within the designated range and the density around the cup was evaluated both in the laboratory and in vivo using the novel laser RFA device. The Kruskal-Wallis test showed robust correlations in both experiments (laboratory study: R = 0.728, p < 0.001; in vivo study: R = 0.619, p < 0.001). Our laser RFA system can assess the quality of bone surrounding the cup. Laser RFA holds promise in predicting the risk of loosening and might aid in the decision-making process for additional fixation through screw insertion.
摘要：
共振频率分析（RFA）对于评估植入物状态很有价值。在之前的调查中,使用激光RFA评估髋臼杯固定，并在体外环境中预测下拉力。虽然下拉力足以进行初始固定评估，需要评估基础的骨强度以进行后续固定。骨骼质量下降会导致微动，迁移,和持久的骨整合，因此，提高了假体周围骨折和内在骨小梁骨失效的敏感性。关于使用RFA评估杯子周围的骨矿物质密度（BMD）的研究有限。对于激光RFA的体内应用，我们实现了扫描脉冲激发方法，并设计了一种创新的激光RFA设备，具有低激光能量和小尺寸。我们专注于特定的频率范围（2500-4500Hz），其中峰值频率被认为受基础密度的影响。使用体模进行定量计算机断层扫描来评估假体周围的BMD。使用新型激光RFA设备在实验室和体内评估指定范围内的共振频率与杯子周围的密度之间的相关性。Kruskal-Wallis检验在两个实验中均显示出稳健的相关性(实验室研究:R=0.728,p<0.001;体内研究:R=0.619,p<0.001)。我们的激光RFA系统可以评估杯子周围骨骼的质量。激光RFA有望预测松动的风险，并可能有助于通过螺钉插入进行额外固定的决策过程。
