Abstract:
Functional neurological disorder (FND) is a common neurologic disorder associated with many comorbid symptoms including fatigue, pain, headache, and orthostasis. These concurrent symptoms lead patients to accumulate multiple diagnoses comorbid with FND, including fibromyalgia, chronic fatigue syndrome, postural orthostatic tachycardia syndrome, persistent post-concussive symptoms, and chronic pain. The role of physical activity and exercise has not been evaluated in FND populations, though has been studied in certain comorbid conditions. In this traditional narrative literature review, we highlight some existing literature on physical activity in FND, then look to comorbid disorders to highlight the therapeutic potential of physical activity. We then consider abnormalities in the autonomic nervous system (ANS) as a potential pathophysiological explanation for symptoms in FND and comorbid disorders and postulate how physical activity and exercise may provide benefit via autonomic regulation.
摘要:
功能性神经障碍(FND)是一种常见的神经系统疾病,与许多共病症状相关,包括疲劳,疼痛,头痛,和矫正。这些并发症状导致患者与FND共病,包括纤维肌痛,慢性疲劳综合征,体位性心动过速综合征,持续的脑震荡后症状,和慢性疼痛。体力活动和锻炼的作用尚未在FND人群中得到评估,尽管已经在某些合并症条件下进行了研究。在这种传统的叙事文献综述中,我们重点介绍了一些关于FND体力活动的现有文献,然后寻找合并症,以突出身体活动的治疗潜力。然后,我们将自主神经系统(ANS)的异常视为FND和合并症症状的潜在病理生理解释,并假设身体活动和运动如何通过自主调节提供益处。