Abstract：
There is an increasing need for new treatment regimens to combat antibiotic-resistant strains of bacteria. Staphylococcus aureus is a clinically important, opportunist pathogen that has developed resistance to a range of antibiotics. The zebrafish larval model of systemic disease has been increasingly utilized to elucidate S. aureus virulence mechanisms and host-pathogen interactions. Here, we outline how this model can be used to investigate the effects of different antibiotics alone and in combination against S. aureus.
摘要：
越来越需要新的治疗方案来对抗抗生素抗性细菌菌株。金黄色葡萄球菌是一种临床上重要的、对一系列抗生素产生抗药性的机会主义病原体。系统疾病的斑马鱼幼虫模型已越来越多地用于阐明金黄色葡萄球菌的毒力机制和宿主-病原体相互作用。这里,我们概述了该模型如何用于研究不同抗生素单独和联合使用对金黄色葡萄球菌的作用.
