{Reference Type}: Journal Article
{Title}: Using the Zebrafish Larval Model of Infection to Investigate Antibiotic Efficacy and Combination Treatments Against Staphylococcus aureus.
{Author}: Tooke AK;Foster SJ;
{Journal}: Methods Mol Biol
{Volume}: 2833
{Issue}: 0
{Year}: 2024
暂无{DOI}: 10.1007/978-1-0716-3981-8_1
{Abstract}: There is an increasing need for new treatment regimens to combat antibiotic-resistant strains of bacteria. Staphylococcus aureus is a clinically important, opportunist pathogen that has developed resistance to a range of antibiotics. The zebrafish larval model of systemic disease has been increasingly utilized to elucidate S. aureus virulence mechanisms and host-pathogen interactions. Here, we outline how this model can be used to investigate the effects of different antibiotics alone and in combination against S. aureus.