PDF(Pubmed)
Abstract：
UNASSIGNED: To evaluate the relationships among morphology, fundus autofluorescence (FAF), and retinal sensitivity of photocoagulated lesions more than 1 year after panretinal photocoagulation in patients with proliferative diabetic retinopathy and good vision.
UNASSIGNED: This retrospective cohort study included patients with proliferative diabetic retinopathy who had undergone panretinal photocoagulation more than 1 year ago. The photocoagulated lesions were classified according to FAF levels: group A, no FAF; group B, diffuse FAF; group C, white-dotted centers with diffuse FAF; group D, white-dotted centers without FAF; and group E, controls. The main outcome measures were FAF, retinal sensitivity, and morphology of the photocoagulated lesions.
UNASSIGNED: The median sensitivity values and number of photocoagulated lesions in groups A (n = 37), B (n = 39), C (n = 4), D (n = 15), and E (n = 39) were 0 dB, 18.0 dB, 13.9 dB, 0.3 dB, and 21.5 dB, respectively. EZ lines were absent in 93.5%, 18.1%, 50%, 93.3%, and 0% of lesions in groups A, B, C, D, and E, respectively. The inner retinal layer was damaged in 45.2%, 3.0%, 50%, 73.3%, and 0% lesions in groups A, B, C, D, and E, respectively. Statistically significant between-group differences were observed in the retinal sensitivities of the photocoagulated lesions, presence of EZ lines, and damage to the inner retinal layer (p < 0.05).
UNASSIGNED: The photoreceptors in most photocoagulated lesions with diffuse FAF retain their morphology and function.
UNASSIGNED: Using fundus autofluorescence, the damage to photoreceptors after panretinal photocoagulation in patients with diabetes can be estimated in a noninvasive manner. This process can help in determining the need for additional panretinal photocoagulation.
UNASSIGNED: This retrospective cohort study included patients with proliferative diabetic retinopathy who had undergone panretinal photocoagulation more than 1 year ago. The photocoagulated lesions were classified according to FAF levels: group A, no FAF; group B, diffuse FAF; group C, white-dotted centers with diffuse FAF; group D, white-dotted centers without FAF; and group E, controls. The main outcome measures were FAF, retinal sensitivity, and morphology of the photocoagulated lesions.
UNASSIGNED: The median sensitivity values and number of photocoagulated lesions in groups A (n = 37), B (n = 39), C (n = 4), D (n = 15), and E (n = 39) were 0 dB, 18.0 dB, 13.9 dB, 0.3 dB, and 21.5 dB, respectively. EZ lines were absent in 93.5%, 18.1%, 50%, 93.3%, and 0% of lesions in groups A, B, C, D, and E, respectively. The inner retinal layer was damaged in 45.2%, 3.0%, 50%, 73.3%, and 0% lesions in groups A, B, C, D, and E, respectively. Statistically significant between-group differences were observed in the retinal sensitivities of the photocoagulated lesions, presence of EZ lines, and damage to the inner retinal layer (p < 0.05).
UNASSIGNED: The photoreceptors in most photocoagulated lesions with diffuse FAF retain their morphology and function.
UNASSIGNED: Using fundus autofluorescence, the damage to photoreceptors after panretinal photocoagulation in patients with diabetes can be estimated in a noninvasive manner. This process can help in determining the need for additional panretinal photocoagulation.
摘要：
■为了评估形态学之间的关系，眼底自发荧光（FAF），增殖性糖尿病视网膜病变患者在全视网膜光凝术后1年以上对光凝病变的视网膜敏感性和良好视力。
■这项回顾性队列研究纳入了1年前接受全视网膜光凝治疗的增生性糖尿病视网膜病变患者。光凝病变根据FAF水平分类：A组，无FAF；B组，弥漫性FAF；C组，带有弥漫性FAF的白点中心；D组，没有FAF的白点中心；和E组，controls.主要结果指标是FAF，视网膜敏感性,和光凝病变的形态。
■A组（n=37）的中位值和光凝病变的数量，B（n=39），C(n=4),D(n=15),E(n=39)为0dB，18.0dB,13.9dB,0.3dB,和21.5dB，分别。在93.5%中没有EZ系，18.1%,50%,93.3%,A组有0%的病变，B,C,D,E,分别。45.2%的视网膜内层受损,3.0%,50%,73.3%,A组有0%的病变，B,C,D,E,分别。在光凝病变的视网膜敏感性方面观察到有统计学意义的组间差异，EZ线的存在，对视网膜内层的损伤(p<0.05)。
■大多数具有弥漫性FAF的光凝性病变中的光感受器保留了其形态和功能。
■使用眼底自发荧光，糖尿病患者全视网膜光凝术后对光感受器的损害可以通过非侵入性的方式进行评估.该过程可以帮助确定对额外的全视网膜光凝的需要。
■这项回顾性队列研究纳入了1年前接受全视网膜光凝治疗的增生性糖尿病视网膜病变患者。光凝病变根据FAF水平分类：A组，无FAF；B组，弥漫性FAF；C组，带有弥漫性FAF的白点中心；D组，没有FAF的白点中心；和E组，controls.主要结果指标是FAF，视网膜敏感性,和光凝病变的形态。
■A组（n=37）的中位值和光凝病变的数量，B（n=39），C(n=4),D(n=15),E(n=39)为0dB，18.0dB,13.9dB,0.3dB,和21.5dB，分别。在93.5%中没有EZ系，18.1%,50%,93.3%,A组有0%的病变，B,C,D,E,分别。45.2%的视网膜内层受损,3.0%,50%,73.3%,A组有0%的病变，B,C,D,E,分别。在光凝病变的视网膜敏感性方面观察到有统计学意义的组间差异，EZ线的存在，对视网膜内层的损伤(p<0.05)。
■大多数具有弥漫性FAF的光凝性病变中的光感受器保留了其形态和功能。
■使用眼底自发荧光，糖尿病患者全视网膜光凝术后对光感受器的损害可以通过非侵入性的方式进行评估.该过程可以帮助确定对额外的全视网膜光凝的需要。
