Abstract：
OBJECTIVE: To analyse the preva lence of complications related to out-of-hospital cardiac arrest patients achieving target temperature management within 360 minutes compared to those taking more than 360 minutes.
METHODS: The retrospective study was conducted at a medical centre in Taiwan, and comprised data from Januar y 1, 2014, to December 31, 2020. Data was retrieved using the International Classification of Diseases version 10 codes I46.2, I46.8 and I46.9 related to adult patients of either gender presenting to the Emergenc y Medicine department with out-of-hospital cardiac arrest. Data included gender, age, medical histor y, body mass index, acute physiology and chronic health evaluation II score, blood glucose levels, electrocardiogram results, and complications occurring within the target temperature management timeframe. Data was divided into group A having patients who achieved target temperature management within 360 minutes, and group B having patients with delayed TTM of more than 360 minutes. Data was analysed using SPSS 22.
RESULTS: Of the 127 patients, 76(59%) were males, 51(41%) were females,, 47(37%) were aged >75 years, and 13(10.3%) were aged <50 years. Of the total, 65(51.2%) patients were in group A, and 62(48.8%) were in group B. Pneumonia, urinary tract infection, septic shock and gastrointestinal bleeding had lower incidence rates in group A than group B (p<0.05). The odds of death were 2.879 times high er in group B patients than group A (95% confidence interval: 1.908-8.916).
CONCLUSIONS: Hypothermia tre atment should be sta rted as soon as pos sible to achieve target temp erature management within 360 minutes to reduce the risk of complications and mortality.
METHODS: The retrospective study was conducted at a medical centre in Taiwan, and comprised data from Januar y 1, 2014, to December 31, 2020. Data was retrieved using the International Classification of Diseases version 10 codes I46.2, I46.8 and I46.9 related to adult patients of either gender presenting to the Emergenc y Medicine department with out-of-hospital cardiac arrest. Data included gender, age, medical histor y, body mass index, acute physiology and chronic health evaluation II score, blood glucose levels, electrocardiogram results, and complications occurring within the target temperature management timeframe. Data was divided into group A having patients who achieved target temperature management within 360 minutes, and group B having patients with delayed TTM of more than 360 minutes. Data was analysed using SPSS 22.
RESULTS: Of the 127 patients, 76(59%) were males, 51(41%) were females,, 47(37%) were aged >75 years, and 13(10.3%) were aged <50 years. Of the total, 65(51.2%) patients were in group A, and 62(48.8%) were in group B. Pneumonia, urinary tract infection, septic shock and gastrointestinal bleeding had lower incidence rates in group A than group B (p<0.05). The odds of death were 2.879 times high er in group B patients than group A (95% confidence interval: 1.908-8.916).
CONCLUSIONS: Hypothermia tre atment should be sta rted as soon as pos sible to achieve target temp erature management within 360 minutes to reduce the risk of complications and mortality.
摘要：
目的：分析与那些在360分钟内达到目标体温管理的院外心脏骤停患者相关的并发症的发生率。
方法:回顾性研究是在台湾一家医疗中心进行的,包括2014年1月1日至2020年12月31日的数据。使用国际疾病分类第10版代码I46.2，I46.8和I46.9检索数据，这些数据与因院外心脏骤停而到急诊医学部就诊的任何性别的成年患者有关。数据包括性别，年龄,医学组织学y，身体质量指数,急性生理和慢性健康评估II评分，血糖水平，心电图结果,以及在目标温度管理时间范围内发生的并发症。数据分为A组，其中患者在360分钟内达到目标体温管理，B组有延迟TTM超过360分钟的患者。数据采用SPSS22进行分析。
结果：在127例患者中，76（59％）是男性，51（41%）是女性，,47（37%）年龄>75岁，13人(10.3%)年龄<50岁。在总数中，A组65例(51.2%),B组肺炎62例(48.8%),尿路感染,A组感染性休克和消化道出血发生率低于B组(p<0.05)。B组患者的死亡几率是A组的2.879倍（95％置信区间：1.908-8.916）。
结论：应尽快进行低温治疗，以在360分钟内达到目标温度管理，以降低并发症和死亡率的风险。
方法:回顾性研究是在台湾一家医疗中心进行的,包括2014年1月1日至2020年12月31日的数据。使用国际疾病分类第10版代码I46.2，I46.8和I46.9检索数据，这些数据与因院外心脏骤停而到急诊医学部就诊的任何性别的成年患者有关。数据包括性别，年龄,医学组织学y，身体质量指数,急性生理和慢性健康评估II评分，血糖水平，心电图结果,以及在目标温度管理时间范围内发生的并发症。数据分为A组，其中患者在360分钟内达到目标体温管理，B组有延迟TTM超过360分钟的患者。数据采用SPSS22进行分析。
结果：在127例患者中，76（59％）是男性，51（41%）是女性，,47（37%）年龄>75岁，13人(10.3%)年龄<50岁。在总数中，A组65例(51.2%),B组肺炎62例(48.8%),尿路感染,A组感染性休克和消化道出血发生率低于B组(p<0.05)。B组患者的死亡几率是A组的2.879倍（95％置信区间：1.908-8.916）。
结论：应尽快进行低温治疗，以在360分钟内达到目标温度管理，以降低并发症和死亡率的风险。
