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Abstract：
Antiphospholipid syndrome (APS) is a systemic autoimmune syndrome characterized by arterial or venous thrombosis, pregnancy complications and thrombocytopenia. The aim of this study is to investigate the association between APS and atrial fibrillation (AF) among patients in Peking University People\'s Hospital. A single center retrospective study was conducted. Cases were hospitalized patients diagnosed with AF by a cardiologist while the control group patients did not exhibit cardiac diseases. The results of the study revealed that in multivariable logistic regression, APS, anticardiolipin antibody (aCL) positivity and anti-beta-2-glycoprotein antibody (anti-β2GPI) positivity are independent risk factors of AF. APS, aCL positivity and anti-β 2GPI positivity are statistically different between AF patients and non-AF patients. Forthcoming studies are needed to clarify the potential link between APS and AF.
摘要：
抗磷脂综合征（APS）是一种以动脉或静脉血栓形成为特征的全身性自身免疫综合征，妊娠并发症和血小板减少症。本研究旨在探讨北京大学人民医院患者APS与心房颤动(AF)的关系。进行单中心回顾性研究。病例为心脏病专家诊断为房颤的住院患者，而对照组患者未出现心脏病。研究结果表明，在多变量逻辑回归中，APS,抗心磷脂抗体（aCL）阳性和抗β-2-糖蛋白抗体（抗β2GPI）阳性是房颤的独立危险因素。APS,aCL阳性和抗β2GPI阳性在AF患者和非AF患者之间有统计学差异。接下来的研究需要阐明APS和AF之间的潜在联系。
