PDF(Pubmed)
Abstract：
UNASSIGNED: Low back pain (LBP) is the most frequent indication to magnetic resonance imaging (MRI) examinations of the lumbosacral spine. The individual role of soft tissues, including muscles, on LBP is not fully understood and the contribution of each MRI-derived parameter of soft tissues status on the intensity of LBP has not been investigated in detail.
UNASSIGNED: The study design was observational retrospective, single center carried out at a University Hospital. Images were acquired using a using a 1.5 Tesla scanner. Patients completed a symptom questionnaire and rated their pain intensity using the Visual Analogue Scale (VAS). The VAS scores were categorized as mild, moderate, and severe using cutoff values of 3.8 and 5.7, based on the literature. Biometric data, including weight and height, were also recorded to calculate the body mass index (BMI). The ratios between intramuscular fat infiltration and net muscle area were also calculated. Patient sample included 94 patients with LBP underwent MRI of the lumbosacral spine.
UNASSIGNED: The stepwise analysis revealed that increasing psoas net area was associated with lower VAS levels (odds ratio [OR]: 0.94: 95% confidence interval [CI]: 0.90-0.98; p=.005), and an increase of one square centimeter of total psoas area resulted in a greater probability of reporting a mild (+1.21%; 95% CI: 0.37, 2.05%) or a moderate VAS (+0.40%; 95% CI: -0.02, 0.82%), Furthermore, a more severe VAS was associated with a higher BMI (OR: 1.13; 95% CI: 1.00-1.27).
UNASSIGNED: Our study demonstrates a relationship between LBP and MRI parameters of paravertebral and psoas muscles status. The psoas muscle is extremely important for spine stabilization and is linked to clinical symptoms of patients affected by LBP. These findings could contribute to future studies and improve treatment options in patients with LBP, possibly reducing the impact on disability, quality of life and socioeconomical burden.
UNASSIGNED: The study design was observational retrospective, single center carried out at a University Hospital. Images were acquired using a using a 1.5 Tesla scanner. Patients completed a symptom questionnaire and rated their pain intensity using the Visual Analogue Scale (VAS). The VAS scores were categorized as mild, moderate, and severe using cutoff values of 3.8 and 5.7, based on the literature. Biometric data, including weight and height, were also recorded to calculate the body mass index (BMI). The ratios between intramuscular fat infiltration and net muscle area were also calculated. Patient sample included 94 patients with LBP underwent MRI of the lumbosacral spine.
UNASSIGNED: The stepwise analysis revealed that increasing psoas net area was associated with lower VAS levels (odds ratio [OR]: 0.94: 95% confidence interval [CI]: 0.90-0.98; p=.005), and an increase of one square centimeter of total psoas area resulted in a greater probability of reporting a mild (+1.21%; 95% CI: 0.37, 2.05%) or a moderate VAS (+0.40%; 95% CI: -0.02, 0.82%), Furthermore, a more severe VAS was associated with a higher BMI (OR: 1.13; 95% CI: 1.00-1.27).
UNASSIGNED: Our study demonstrates a relationship between LBP and MRI parameters of paravertebral and psoas muscles status. The psoas muscle is extremely important for spine stabilization and is linked to clinical symptoms of patients affected by LBP. These findings could contribute to future studies and improve treatment options in patients with LBP, possibly reducing the impact on disability, quality of life and socioeconomical burden.
摘要：
■下腰痛（LBP）是腰骶脊柱磁共振成像（MRI）检查的最常见指征。软组织的个体作用，包括肌肉,对LBP的影响尚未完全了解，并且尚未详细研究每个MRI得出的软组织状态参数对LBP强度的贡献。
■研究设计是观察性回顾性研究，在大学医院进行的单一中心。使用1.5特斯拉扫描仪获取图像。患者完成症状问卷并使用视觉模拟量表（VAS）评估其疼痛强度。VAS评分被归类为轻度，中度,根据文献，使用3.8和5.7的截止值进行严重。生物识别数据，包括体重和身高,还记录了体重指数（BMI）。还计算了肌内脂肪浸润与净肌肉面积之间的比率。患者样本包括94例LBP患者，接受了腰骶脊柱MRI检查。
■逐步分析表明，腰大净面积的增加与较低的VAS水平相关（比值比[OR]：0.94：95％置信区间[CI]：0.90-0.98；p=.005），并且总腰大肌面积增加一平方厘米导致报告轻度（+1.21%；95%CI：0.37，2.05%）或中度VAS（+0.40%；95%CI：-0.02，0.82%）的可能性更大，此外，更严重的VAS与更高的BMI相关(OR:1.13;95%CI:1.00-1.27).
■我们的研究表明了LBP与椎旁肌和腰大肌状态的MRI参数之间的关系。腰大肌对于脊柱稳定极为重要，并且与受LBP影响的患者的临床症状有关。这些发现可能有助于未来的研究和改善LBP患者的治疗选择。可能减少对残疾的影响，生活质量和社会经济负担。
■研究设计是观察性回顾性研究，在大学医院进行的单一中心。使用1.5特斯拉扫描仪获取图像。患者完成症状问卷并使用视觉模拟量表（VAS）评估其疼痛强度。VAS评分被归类为轻度，中度,根据文献，使用3.8和5.7的截止值进行严重。生物识别数据，包括体重和身高,还记录了体重指数（BMI）。还计算了肌内脂肪浸润与净肌肉面积之间的比率。患者样本包括94例LBP患者，接受了腰骶脊柱MRI检查。
■逐步分析表明，腰大净面积的增加与较低的VAS水平相关（比值比[OR]：0.94：95％置信区间[CI]：0.90-0.98；p=.005），并且总腰大肌面积增加一平方厘米导致报告轻度（+1.21%；95%CI：0.37，2.05%）或中度VAS（+0.40%；95%CI：-0.02，0.82%）的可能性更大，此外，更严重的VAS与更高的BMI相关(OR:1.13;95%CI:1.00-1.27).
■我们的研究表明了LBP与椎旁肌和腰大肌状态的MRI参数之间的关系。腰大肌对于脊柱稳定极为重要，并且与受LBP影响的患者的临床症状有关。这些发现可能有助于未来的研究和改善LBP患者的治疗选择。可能减少对残疾的影响，生活质量和社会经济负担。
