PDF(Pubmed)
Abstract：
The One Health approach, which integrates the health of humans, animals, plants, and ecosystems at various levels, is crucial for addressing interconnected health threats. This is complemented by the advent of mRNA vaccines, which have revolutionized disease prevention. They offer broad-spectrum effectiveness and can be rapidly customized to target specific pathogens. Their utility extends beyond human medicine, showing potential in veterinary practices to control diseases and reduce the risk of zoonotic transmissions. This review place mRNA vaccines and One Health in the context of tick-borne diseases. The potential of these vaccines to confer cross-species immunity is significant, potentially disrupting zoonotic disease transmission cycles and protecting the health of both humans and animals, while reducing tick populations, infestations and circulation of pathogens. The development and application of mRNA vaccines for tick and tick-borne pathogens represent a comprehensive strategy in global health, fostering a healthier ecosystem for all species in our interconnected world.
摘要：
一个健康的方法，它整合了人类的健康，动物,植物,和不同层次的生态系统，对于解决相互关联的健康威胁至关重要。mRNA疫苗的出现补充了这一点，彻底改变了疾病预防。它们提供广谱的有效性，可以快速定制以靶向特定的病原体。它们的用途超越了人类医学，在兽医实践中显示出控制疾病和降低人畜共患传播风险的潜力。这篇综述将mRNA疫苗和一个健康放在蜱传疾病的背景下。这些疫苗赋予跨物种免疫力的潜力是巨大的，可能破坏人畜共患疾病的传播周期并保护人类和动物的健康，在减少蜱种群的同时，病原体的感染和循环。蜱和蜱传病原体mRNA疫苗的开发和应用代表了全球卫生的综合战略，在我们相互联系的世界中，为所有物种培育更健康的生态系统。
