Abstract：
The chemical investigation of the methanol trunk bark extract of Erythrina senegalensis led to the isolation of a new flavanone, 5,7,4\'-trihydroxy-3\',5\'-bis(3-methylbutadienyl)flavanone (trivially named senegalensisnone) (1), together with seven known compounds, abyssinone-V-4\'-O-methyl ether (2), abyssinone V (3), Calopocarpin (4), genistein (5) mixture of stigmasterol (6) and β-sitosterol (7) and β-sitosterol-3-O-β-D-glucopyranoside (8). The structures of the isolates were elucidated by extensive spectroscopic and spectrometric analyses (1D and 2D NMR, ESI-MS) and by comparison with previously reported data. The absolute configuration of 1 was deduced based on comparison of its experimental CD with that of similar compound. All the compounds were tested for their antibacterial, antifungal and antioxidant activities. Compound 4 displayed weak antibacterial activity against Salmonella enteritidis with MIC value of 62.5 μg/mL. All the isolates were found to be inactive as antioxidant agents in the DPPH, ABTS and FRAP assays.
摘要：
通过对七叶草甲醇树皮提取物的化学研究，分离出了一种新的黄烷酮，5,7,4\'-三羟基-3\',5'-双（3-甲基丁二烯基）黄烷酮（三重命名为苯丙酮）（1），连同七种已知的化合物，苦参素-V-4'-O-甲基醚（2），苦参素V(3),Calopocarpin(4),金雀异黄素(5)豆甾醇(6)和β-谷甾醇(7)和β-谷甾醇-3-O-β-D-吡喃葡萄糖苷(8)的混合物。通过广泛的光谱和光谱分析（1D和2DNMR，ESI-MS)，并与以前报告的数据进行比较。1的绝对构型是基于其实验CD与类似化合物的CD的比较来推导的。所有化合物都经过了抗菌测试，抗真菌和抗氧化活性。化合物4对肠炎沙门氏菌表现出弱的抗菌活性,MIC值为62.5μg/mL。发现所有分离物在DPPH中作为抗氧化剂是无活性的，ABTS和FRAP测定。
