%0 Journal Article
%T New flavanone and other constituents from erythrina senegalensis A. DC. (fabaceae).
%A Tadjong Tcho A
%A Djouaka Bavoua JL
%A Ngouonpe Wembe A
%A Gompe Bobda EG
%A Majoumo F
%A Leuche JM
%A Ndonfack Tiofack E
%A Mbah JA
%A Toze FAA
%J Nat Prod Res
%V 0
%N 0
%D 2024 Jul 1
%M 38946337
%F 2.488
%R 10.1080/14786419.2024.2364258
%X The chemical investigation of the methanol trunk bark extract of Erythrina senegalensis led to the isolation of a new flavanone, 5,7,4'-trihydroxy-3',5'-bis(3-methylbutadienyl)flavanone (trivially named senegalensisnone) (1), together with seven known compounds, abyssinone-V-4'-O-methyl ether (2), abyssinone V (3), Calopocarpin (4), genistein (5) mixture of stigmasterol (6) and β-sitosterol (7) and β-sitosterol-3-O-β-D-glucopyranoside (8). The structures of the isolates were elucidated by extensive spectroscopic and spectrometric analyses (1D and 2D NMR, ESI-MS) and by comparison with previously reported data. The absolute configuration of 1 was deduced based on comparison of its experimental CD with that of similar compound. All the compounds were tested for their antibacterial, antifungal and antioxidant activities. Compound 4 displayed weak antibacterial activity against Salmonella enteritidis with MIC value of 62.5 μg/mL. All the isolates were found to be inactive as antioxidant agents in the DPPH, ABTS and FRAP assays.