PDF(Pubmed)
Abstract：
An 8-year-old Portuguese Water Dog presented with a 5-month history of left forelimb lameness. There was palmar pain. Ultrasonography revealed enlargement of the left median nerve. Subsequent MRI also showed enlargement of the median nerve in the distal palmar to the mid-forearm region. Rapid intraoperative diagnosis suggested malignant peripheral nerve sheath tumors (MPNST) and a neurotomy was performed. The lameness had almost disappeared in 1 month after surgery. Recurrence occurred 26 months postoperatively and the forelimb was amputated. At 950 days after the neurotomy, radiography revealed lung metastasis, and the dog died 988 days after the neurotomy. Neurotomy for MPNST should be performed with caution until more information is available regarding methods for early detection, margin determination, and indication determination for neurotomy.
摘要：
一只8岁的葡萄牙水犬，有5个月的左前肢跛行史。手掌疼痛。超声检查显示左正中神经增大。随后的MRI还显示手掌远端至前臂中部的正中神经增大。术中快速诊断提示恶性周围神经鞘瘤（MPNST）并进行神经切开术。跛行在手术后1个月几乎消失。术后26个月复发，前肢截肢。神经切断术后950天，X线摄影显示肺转移，狗在神经切断术后988天死亡。在获得有关早期检测方法的更多信息之前，应谨慎进行MPNST的神经切断术。保证金确定，和神经切断术的适应症确定。
