Abstract：
BACKGROUND: COPD has become more prevalent among women, revealing a specific feminine phenotype. Women experience greater dyspnea and a more impaired quality of life. The main objective of this study was to assess the effect of gender on dyspnea during a pulmonary rehabilitation program (PRP).
METHODS: Retrospective study including COPD patients having participated in PRPs. The following data were analyzed according to gender before and after a PRP: dyspnea, quality of life, anxiety and depression, exercise capacity, muscle function (quadriceps and inspiratory muscles).
RESULTS: More than 500 patients (252 men and 252 women) were included. We did not find a significant effect of gender on the evolution of dyspnea, anxiety or depressive disorders, exercise capacity, inspiratory muscle strength, or overall quality of life score. That said, we found a possible effect on the sub-scores of the quality of life questionnaire, and regarding quadriceps strength. All criteria improved during the program in both groups.
CONCLUSIONS: During a PRP, gender does not impact the evolution of dyspnea. While women may nonetheless benefit to a greater extent in terms of quality of life sub-scores (impact, activities, symptoms) and quadriceps strength, these results still require confirmation.
METHODS: Retrospective study including COPD patients having participated in PRPs. The following data were analyzed according to gender before and after a PRP: dyspnea, quality of life, anxiety and depression, exercise capacity, muscle function (quadriceps and inspiratory muscles).
RESULTS: More than 500 patients (252 men and 252 women) were included. We did not find a significant effect of gender on the evolution of dyspnea, anxiety or depressive disorders, exercise capacity, inspiratory muscle strength, or overall quality of life score. That said, we found a possible effect on the sub-scores of the quality of life questionnaire, and regarding quadriceps strength. All criteria improved during the program in both groups.
CONCLUSIONS: During a PRP, gender does not impact the evolution of dyspnea. While women may nonetheless benefit to a greater extent in terms of quality of life sub-scores (impact, activities, symptoms) and quadriceps strength, these results still require confirmation.
摘要：
背景：COPD在女性中越来越普遍，揭示特定的女性表型。女性经历更大的呼吸困难和更受损的生活质量。这项研究的主要目的是评估性别对肺康复计划（PRP）期间呼吸困难的影响。
方法：包括参与PRP的COPD患者的回顾性研究。根据PRP前后的性别分析以下数据：呼吸困难，生活质量,焦虑和抑郁,锻炼能力,肌肉功能（股四头肌和吸气肌）。
结果：纳入了500多名患者（252名男性和252名女性）。我们没有发现性别对呼吸困难的演变有显著影响，焦虑或抑郁障碍，锻炼能力,吸气肌肉力量，或整体生活质量评分。那就是说,我们发现可能对生活质量问卷的子得分有影响，关于股四头肌的力量。两组的所有标准在程序中都得到了改善。
结论：在PRP期间，性别不影响呼吸困难的演变。虽然女性可能在更大程度上受益于生活质量分(影响，活动,症状)和股四头肌力量，这些结果仍然需要确认。
方法：包括参与PRP的COPD患者的回顾性研究。根据PRP前后的性别分析以下数据：呼吸困难，生活质量,焦虑和抑郁,锻炼能力,肌肉功能（股四头肌和吸气肌）。
结果：纳入了500多名患者（252名男性和252名女性）。我们没有发现性别对呼吸困难的演变有显著影响，焦虑或抑郁障碍，锻炼能力,吸气肌肉力量，或整体生活质量评分。那就是说,我们发现可能对生活质量问卷的子得分有影响，关于股四头肌的力量。两组的所有标准在程序中都得到了改善。
结论：在PRP期间，性别不影响呼吸困难的演变。虽然女性可能在更大程度上受益于生活质量分(影响，活动,症状)和股四头肌力量，这些结果仍然需要确认。
