Abstract：
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are the two most bariatric procedures in Asia. However, a comparison of long-term outcomes is still limited.
OBJECTIVE: To compare the degree of long-term weight loss, remission of comorbidities and complication rates after LRYGB and LSG procedures.
METHODS: A retrospective analysis was conducted for all patients who underwent LSG or LRYGB between May 2005 and May 2018 at a single institute with at least 1-5 years of follow up. Demographic data were collected.
RESULTS: Of the total 342 patients, 159 underwent primary LSG and 183 patients underwent LRYGB. Preoperative BMI in the LSG group was significantly higher than the LRYGB group (54.7 ± 12.6 kg/m2 vs 48.2 ± 8.2 kg/m2, P = 0.001). Comorbidities between LSG and LRYGB groups were similar. Mean percentage of total weight loss (%TWL) at 5 years after was 23.6 ± 1.7 % in the LSG group vs. 29.9 ± 1.3 % in the LRYGB group (P = 0.005) and LRYGB resulted in greater weight loss than LSG at all time points. The remission of comorbidities were similar in both groups, except that dyslipidemia was significantly better in the LRYGB group. Overall complications were 35.2 % in the LSG group vs. 20.8 % in the LRYGB group (P = 0.003).
CONCLUSIONS: Our center revealed that LRYGB had better results than LSG in terms of percentage total weight loss at all time points. In the long term, LSG showed a higher overall complication rate compared to LRYGB.
OBJECTIVE: To compare the degree of long-term weight loss, remission of comorbidities and complication rates after LRYGB and LSG procedures.
METHODS: A retrospective analysis was conducted for all patients who underwent LSG or LRYGB between May 2005 and May 2018 at a single institute with at least 1-5 years of follow up. Demographic data were collected.
RESULTS: Of the total 342 patients, 159 underwent primary LSG and 183 patients underwent LRYGB. Preoperative BMI in the LSG group was significantly higher than the LRYGB group (54.7 ± 12.6 kg/m2 vs 48.2 ± 8.2 kg/m2, P = 0.001). Comorbidities between LSG and LRYGB groups were similar. Mean percentage of total weight loss (%TWL) at 5 years after was 23.6 ± 1.7 % in the LSG group vs. 29.9 ± 1.3 % in the LRYGB group (P = 0.005) and LRYGB resulted in greater weight loss than LSG at all time points. The remission of comorbidities were similar in both groups, except that dyslipidemia was significantly better in the LRYGB group. Overall complications were 35.2 % in the LSG group vs. 20.8 % in the LRYGB group (P = 0.003).
CONCLUSIONS: Our center revealed that LRYGB had better results than LSG in terms of percentage total weight loss at all time points. In the long term, LSG showed a higher overall complication rate compared to LRYGB.
摘要：
背景：腹腔镜袖状胃切除术（LSG）和腹腔镜Roux-en-Y胃旁路术（LRYGB）是亚洲两种最肥胖的手术。然而,长期结局的比较仍然有限.
目的：为了比较长期体重减轻的程度，LRYGB和LSG手术后合并症和并发症发生率的缓解。
方法：对所有在2005年5月至2018年5月期间接受LSG或LRYGB的患者进行回顾性分析，随访至少1-5年。收集人口统计数据。
结果：在总共342名患者中，159例患者接受了原发性LSG，183例患者接受了LRYGB。LSG组术前BMI显著高于LRYGB组(54.7±12.6kg/m2vs48.2±8.2kg/m2,P=0.001)。LSG和LRYGB组之间的合并症相似。LSG组5年后的平均总体重减轻百分比（％TWL）为23.6±1.7％LRYGB组的29.9±1.3%(P=0.005)和LRYGB在所有时间点均导致比LSG更大的体重减轻。两组合并症的缓解情况相似，除了LRYGB组的血脂异常明显更好。LSG组的总并发症为35.2%。LRYGB组为20.8%(P=0.003)。
结论：我们的中心显示，就所有时间点的总重量损失百分比而言，LRYGB比LSG具有更好的结果。从长远来看,与LRYGB相比，LSG显示出更高的总体并发症发生率。
目的：为了比较长期体重减轻的程度，LRYGB和LSG手术后合并症和并发症发生率的缓解。
方法：对所有在2005年5月至2018年5月期间接受LSG或LRYGB的患者进行回顾性分析，随访至少1-5年。收集人口统计数据。
结果：在总共342名患者中，159例患者接受了原发性LSG，183例患者接受了LRYGB。LSG组术前BMI显著高于LRYGB组(54.7±12.6kg/m2vs48.2±8.2kg/m2,P=0.001)。LSG和LRYGB组之间的合并症相似。LSG组5年后的平均总体重减轻百分比（％TWL）为23.6±1.7％LRYGB组的29.9±1.3%(P=0.005)和LRYGB在所有时间点均导致比LSG更大的体重减轻。两组合并症的缓解情况相似，除了LRYGB组的血脂异常明显更好。LSG组的总并发症为35.2%。LRYGB组为20.8%(P=0.003)。
结论：我们的中心显示，就所有时间点的总重量损失百分比而言，LRYGB比LSG具有更好的结果。从长远来看,与LRYGB相比，LSG显示出更高的总体并发症发生率。
