关键词: Immunoprophylaxis RSV Respiratory syncytial virus Seasonality Surveillance

Mesh : Humans Respiratory Syncytial Virus Infections / epidemiology diagnosis Infant Cost of Illness Child, Preschool Infant, Newborn Respiratory Tract Infections / epidemiology diagnosis virology Respiratory Syncytial Virus, Human Antiviral Agents / therapeutic use Risk Factors Global Health

来  源:   DOI:10.1016/j.yapd.2024.02.003

Abstract:
Respiratory syncytial virus (RSV) is a common viral pathogen that accounts about 33 million cases of acute lower respiratory tract infection (LRTI) worldwide in children under the age of 5 years each year. High-risk populations, particularly preterm infants, those with underlying chronic lung disease, congenital heart disease, or compromised immune systems, are afflicted most significantly. RSV infection is characterized by significant amount of mucus and submucosal edema in the respiratory tract, leading to congestion and, oftentimes, significant respiratory distress. Antigen- and PCR-based testing are used to diagnose RSV infection.
摘要:
呼吸道合胞病毒(RSV)是一种常见的病毒病原体,每年在5岁以下的儿童中,全球约有3300万例急性下呼吸道感染(LRTI)。高危人群,尤其是早产儿,那些患有潜在慢性肺病的人,先天性心脏病,或者免疫系统受损,痛苦最严重。RSV感染的特征是呼吸道有大量粘液和粘膜下水肿,导致拥堵,时常,严重的呼吸窘迫。基于抗原和PCR的检测用于诊断RSV感染。
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