Abstract：
The human body is commonly exposed to bisphenol A (BPA), which is widely used in consumer and industrial products. BPA is an endocrine-disrupting chemical that has adverse effects on human health. In particular, many studies have shown that BPA can cause various neurological disorders by affecting brain development and neural function during prenatal, infancy, childhood, and adulthood exposure. In this review, we discussed the correlation between BPA and neurological disorders based on molecular cell biology, neurophysiology, and behavioral studies of the effects of BPA on brain development and function. Recent studies, both animal and epidemiological, strongly indicate that BPA significantly impacts brain development and function. It hinders neural processes, such as proliferation, migration, and differentiation during development, affecting synaptic formation and activity. As a result, BPA is implicated in neurodevelopmental and neuropsychiatric disorders like autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), and schizophrenia.
摘要：
人体通常暴露于双酚A（BPA），广泛用于消费品和工业产品。BPA是一种干扰内分泌的化学物质，对人体健康有不良影响。特别是,许多研究表明，双酚A可以通过影响产前大脑发育和神经功能而导致各种神经系统疾病，婴儿期,童年,和成年暴露。在这次审查中,我们从分子细胞生物学角度探讨了双酚A与神经系统疾病的相关性,神经生理学，以及BPA对大脑发育和功能影响的行为研究。最近的研究,动物和流行病学，强烈表明BPA显著影响大脑发育和功能。它阻碍了神经过程，如扩散，迁移,和发育过程中的分化，影响突触形成和活动。因此,BPA与神经发育和神经精神疾病有关，如自闭症谱系障碍（ASD），注意缺陷多动障碍（ADHD），和精神分裂症。
