PDF(Pubmed)
Abstract：
UNASSIGNED: Well-known adverse events of antipsychotics are movement disorders, or extrapyramidal symptoms, such as drug-induced parkinsonism and tardive dyskinesia.
UNASSIGNED: With new evidence suggesting a link between low high-density lipoprotein cholesterol (HDL-C) and risk of Parkinson\'s disease, this study sought to investigate if that link also translated to patients taking antipsychotics with low HDL-C and an increased risk for developing a movement disorder.
UNASSIGNED: Adult patients (n=89) at an inpatient state psychiatric facility taking at least one antipsychotic with at least one HDL-C level were assessed for signs of a movement disorder through their history and physical, progress notes, and Abnormal Involuntary Movement Scale (AIMS) score.
UNASSIGNED: There was no statistical significance when comparing a patient\'s movement disorder, AIMS scores, and HDL-C levels to suggest that the HDL-C level influenced a patient\'s movement disorder.
UNASSIGNED: This study did not show a correlation between HDL-C levels and a patient\'s risk of developing a movement disorder while taking an antipsychotic.
UNASSIGNED: With new evidence suggesting a link between low high-density lipoprotein cholesterol (HDL-C) and risk of Parkinson\'s disease, this study sought to investigate if that link also translated to patients taking antipsychotics with low HDL-C and an increased risk for developing a movement disorder.
UNASSIGNED: Adult patients (n=89) at an inpatient state psychiatric facility taking at least one antipsychotic with at least one HDL-C level were assessed for signs of a movement disorder through their history and physical, progress notes, and Abnormal Involuntary Movement Scale (AIMS) score.
UNASSIGNED: There was no statistical significance when comparing a patient\'s movement disorder, AIMS scores, and HDL-C levels to suggest that the HDL-C level influenced a patient\'s movement disorder.
UNASSIGNED: This study did not show a correlation between HDL-C levels and a patient\'s risk of developing a movement disorder while taking an antipsychotic.
摘要：
■众所周知的抗精神病药物不良事件是运动障碍，或者锥体外系症状,如药物诱发的帕金森病和迟发性运动障碍。
■有新的证据表明高密度脂蛋白胆固醇（HDL-C）低与帕金森病的风险之间存在联系，这项研究试图调查这种联系是否也转化为服用抗精神病药物且HDL-C低的患者发生运动障碍的风险增加.
在住院的州立精神病院中服用至少一种HDL-C水平的抗精神病药的成年患者（n=89）通过其病史和身体评估运动障碍的迹象，进度说明，和异常非自愿运动量表(AIMS)得分。
■比较患者的运动障碍时，没有统计学意义，AIMS分数，和HDL-C水平表明HDL-C水平影响患者的运动障碍。
这项研究未显示HDL-C水平与患者服用抗精神病药物时发生运动障碍的风险之间存在相关性。
■有新的证据表明高密度脂蛋白胆固醇（HDL-C）低与帕金森病的风险之间存在联系，这项研究试图调查这种联系是否也转化为服用抗精神病药物且HDL-C低的患者发生运动障碍的风险增加.
在住院的州立精神病院中服用至少一种HDL-C水平的抗精神病药的成年患者（n=89）通过其病史和身体评估运动障碍的迹象，进度说明，和异常非自愿运动量表(AIMS)得分。
■比较患者的运动障碍时，没有统计学意义，AIMS分数，和HDL-C水平表明HDL-C水平影响患者的运动障碍。
这项研究未显示HDL-C水平与患者服用抗精神病药物时发生运动障碍的风险之间存在相关性。
