关键词: ABO genetics gut microbiome metabolite structural variation

来  源:   DOI:10.1016/j.molmed.2024.06.007

Abstract:
The ability of the gut microbiome to adapt to a new environment and utilize a new metabolite or dietary compound by inducing structural variations (SVs) in the genome has an important role in human health. Here, we discuss recent data on host genetic regulation of SV induction and its use as a new therapeutic approach.
摘要:
肠道微生物组通过诱导基因组中的结构变异(SV)来适应新环境并利用新代谢物或膳食化合物的能力在人类健康中具有重要作用。这里,我们讨论了有关SV诱导的宿主遗传调控及其作为新治疗方法的最新数据。
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