Abstract：
This study aimed to evaluate the influence of ultrasonic degradation on the physicochemical and biological characteristics of Polygonatum cyrtonema polysaccharide (PCP, 8.59 kDa). PCP was subjected to ultrasonic treatment for 8, 16, and 24 h and yielded the degraded fractions PCP-8, PCP-16, and PCP-24 (5.06, 4.13, and 3.69 kDa), respectively. Compared with the intact PCP, PCP-8, PCP-16 and PCP-24 had a reduced particle size (decrements of 28.03 %, 46.15 % and 62.54 %, respectively). Although ultrasonic degradation did not alter the primary structure of PCP, its triple helical and superficial structures were disrupted, with degraded fractions demonstrating reduced thermal stability and apparent viscosities compared with those of the intact PCP. Furthermore, the functional properties of the degraded fractions were different. PCP-16 most favourably affected GLP-1 secretion, while PCP-8 and PCP-24 exhibited the strongest antioxidant and enzyme inhibitory activities, respectively. Hence, controlled ultrasound irradiation is an appealing approach for partially degrading PCP and enhancing its bioactivity as a functional agent.
摘要：
本研究旨在评价超声降解对黄精多糖(PCP,8.59kDa）。对PCP进行超声处理8、16和24小时，得到降解的PCP-8、PCP-16和PCP-24（5.06、4.13和3.69kDa）。分别。与完整的PCP相比，PCP-8、PCP-16和PCP-24的粒径减小(减量为28.03%，46.15%和62.54%，分别)。虽然超声波降解并没有改变PCP的主要结构，它的三重螺旋和表面结构被破坏，与完整的PCP相比，降解的馏分显示出降低的热稳定性和表观粘度。此外，降解组分的功能性质不同。PCP-16最有利地影响GLP-1分泌，PCP-8和PCP-24表现出最强的抗氧化和酶抑制活性，分别。因此，受控超声辐照是部分降解PCP并增强其作为功能剂的生物活性的有吸引力的方法。
