关键词: Dysfunction Men Meta-analysis Prevalence Sexual Thyroid gland disorders

来  源:   DOI:10.1007/s40200-024-01408-4   PDF(Pubmed)

Abstract:
UNASSIGNED: fluctuation in serum levels of thyroid hormones or thyroid-associated dysfunction can negatively affect the sexual behaviors or performance, and disruption in couples` relationship or satisfaction. Thus, this systematic review and meta-analysis study was aimed to investigate the global prevalence of sexual dysfunction in men with thyroid gland disorders (TGD).
UNASSIGNED: this systematic review and meta-analysis study conducted based on PRISMA statement criteria regarding the available evidences representing the prevalence of sexual dysfunction in men with TGD. The initial searching process was applied on July, 2023. In this era, the main keywords of \"Prevalence\", \"Sexual disorders\", \"Sexual disorder\", \"Sexual dysfunction\", \"Male sexual dysfunction\", \"Erectile dysfunction\", \"Males\", \"Men\", \"Thyroid disorders\", \"Thyroid diseases\", \"Hyperthyroidism\", \"Thyroid\", and \"Thyroiditis\" were hired. Also, \"AND\" and \"OR\" operators were used for keywords combination. All intended studies were searched using the databases of Web of Science, Google Scholar, Scopus, ScienceDirect, PubMed, and Embase. Random effects model was used to perform the analysis and the heterogeneity of the studies was assessed through I2 index. Data analysis was applied with CMA software (v.2).
UNASSIGNED: following the assessment of 17 eligible studies with a sample size of 501 individuals, the global prevalence of male sexual dysfunction with TGD was found 51.5% (95% CI:38.7-64). Also, the prevalence of male sexual dysfunction in hypothyroidism and hyperthyroidism cases was 59.1% (95% CI:37.2-77.8) and 41.5% (95% CI:25.9-59.1), respectively. The meta-regression analysis showed that following incremental trend in sample size, the global prevalence of male sexual dysfunction with TGD decreases. This assessment also revealed that the prevalence of male sexual dysfunction increases with the year of study conduction, significantly (p < 0.05).
UNASSIGNED: the global prevalence of sexual dysfunction in men with TGD was found relatively high. also, the highest prevalence of sexual disorders was reported in hypothyroid cases. Thus, health policymakers are suggested to inform the individuals prone to this pathology regarding the negative effects of TGD on sexual dysfunction. Besides, TGD-affected cases can prevent sexual disorders and unpleasant consequences through timely medical treatments.
摘要:
血清甲状腺激素水平或甲状腺相关功能障碍的波动会对性行为或行为产生负面影响,以及夫妻关系或满意度的中断。因此,本系统综述和荟萃分析研究旨在调查甲状腺疾病(TGD)男性性功能障碍的全球患病率.
这项系统评价和荟萃分析研究是根据PRISMA陈述标准进行的,该标准涉及代表TGD男性性功能障碍患病率的可用证据。最初的搜索过程是在7月应用的,2023年。在这个时代,“患病率”的主要关键词,“性障碍”,“性障碍”,“性功能障碍”,“男性性功能障碍”,“勃起功能障碍”,\"男性\",\"男人\",“甲状腺疾病”,“甲状腺疾病”,“甲状腺功能亢进”,\"甲状腺\",和“甲状腺炎”被雇佣了。此外,\"AND\"和\"OR\"运算符用于关键字组合。所有预期的研究都是使用WebofScience的数据库进行搜索的,谷歌学者,Scopus,ScienceDirect,PubMed,和Embase。采用随机效应模型进行分析,并通过I2指数评估研究的异质性。数据分析采用CMA软件(v.2)。
对17项符合条件的研究进行评估,样本量为501人,TGD男性性功能障碍的全球患病率为51.5%(95%CI:38.7-64).此外,男性性功能障碍在甲状腺功能减退和甲状腺功能亢进病例中的患病率分别为59.1%(95%CI:37.2-77.8)和41.5%(95%CI:25.9-59.1),分别。荟萃回归分析表明,随着样本量的递增趋势,TGD男性性功能障碍的全球患病率下降。这项评估还显示,男性性功能障碍的患病率随着研究进行的年份而增加,显著(p<0.05)。
发现TGD男性性功能障碍的全球患病率相对较高。还,据报道,在甲状腺功能减退病例中,性功能障碍的患病率最高.因此,建议卫生政策制定者告知容易出现这种病理的个体关于TGD对性功能障碍的负面影响。此外,受TGD影响的病例可以通过及时的药物治疗来预防性功能障碍和不愉快的后果。
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