关键词: American Indians filtration health behaviors injection preparations methamphetamine people who use injection drugs

Mesh : Humans Methamphetamine / administration & dosage Male Female Adult Substance Abuse, Intravenous Filtration Middle Aged Indigenous Peoples Young Adult Interviews as Topic

来  源:   DOI:10.3389/fpubh.2024.1390210   PDF(Pubmed)

Abstract:
UNASSIGNED: Injecting methamphetamine poses significant health risks, but little is known about how methamphetamine injectors filter their injection preparations and experience related health concerns.
UNASSIGNED: A chain-referral sample of Indigenous people who inject methamphetamine (n = 30) was recruited and semistructured interviews were conducted to collect information on filtration practices and health concerns.
UNASSIGNED: Filtration of the injection preparation was described by 53% of injectors. Elevated levels of concern for kidney disease, cancer and heart disease were observed among those who filtered their preparations (ranging from 50 to 56.3%). Concern about liver disease was the most frequent concern among those who filtered their preparations (62.5%) and was elevated in comparison to those who did not use filters (7.1%). Grouped logistic regression revealed a positive association between filtration of the injection preparation and overall health concerns expressed by injectors, after adjusting for gender and age. The marginal posterior distribution of the adjusted odds ratio for filtration of the injection preparation had a posterior median = 35.7, and 95% HPD interval = (5.1, 512.4).
UNASSIGNED: Results illustrate a positive relationship between filtration of the injection preparation and health concerns among Indigenous people who inject methamphetamine. This likely reflects the use of filtration to reduce harms, and further research is needed to understand the full scope of prevention that may be associated with filtration of methamphetamine injection preparations.
摘要:
注射甲基苯丙胺会带来重大的健康风险,但对甲基苯丙胺注射器如何过滤其注射制剂和经历相关健康问题知之甚少。
招募了注射甲基苯丙胺的土著人(n=30)的连锁转诊样本,并进行了半结构化访谈,以收集有关过滤方法和健康问题的信息。
注射制剂的过滤由53%的注射器描述。对肾脏疾病的关注程度升高,在过滤制剂的患者中观察到癌症和心脏病(50%至56.3%)。对肝脏疾病的关注是那些过滤其制剂(62.5%)的人中最常见的关注,并且与不使用过滤器的人(7.1%)相比有所上升。分组逻辑回归显示,注射制剂的过滤与注射器表达的整体健康问题之间存在正相关。在调整性别和年龄后。注射制剂过滤的调整后比值比的边缘后验分布具有后验中位数=35.7,和95%HPD间隔=(5.1,512.4)。
结果表明,注射甲基苯丙胺的土著人民对注射制剂的过滤与健康问题之间存在正相关关系。这可能反映了使用过滤来减少伤害,需要进一步研究以了解可能与甲基苯丙胺注射制剂过滤有关的全部预防范围。
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