关键词: European region disease elimination disease outbreaks epidemiology measles public health surveillance rubella vaccines verification

来  源:   DOI:10.3390/vaccines12060696   PDF(Pubmed)

Abstract:
The elimination of both measles and rubella remains a priority for all 53 Member States of the World Health Organization (WHO) European Region. To provide an update on the epidemiological status of measles and rubella in the Region, we reviewed surveillance data on both diseases for 2023 submitted monthly by national surveillance institutions. We analyzed the cases of measles and rubella for 2023 by age group, case classification, vaccination, hospitalization, and importation status and report on measles-related deaths. In 2023, 60,860 measles cases, including 13 fatal cases, were reported in 41 countries. Most cases (95%; n = 57,584) were reported by six countries: Azerbaijan, Kazakhstan, Kyrgyzstan, Romania, the Russian Federation, and Türkiye. Of the 60,848 cases with data on age, 19,137 (31%) were 1-4 years old and 12,838 (21%) were 5-9 years old. A total of 10,412 (17%) were 20 years and older. The genotypes identified in the Region were largely dominated by D8 variants (n = 1357) and the remainder were B3 variants (n = 221). In 2023, 345 rubella cases were reported by 17 countries, mostly from Poland, Kyrgyzstan, Tajikistan, Türkiye, and Ukraine. A total of 262 cases (76%) were classified as clinically compatible and 79 (23%) were laboratory-confirmed. To achieve the elimination of measles and rubella in the Region, political commitment needs to be revived to enable urgent efforts to increase vaccination coverage, improve surveillance and outbreak preparedness, and respond immediately to outbreaks.
摘要:
消除麻疹和风疹仍然是世界卫生组织(世卫组织)欧洲区域所有53个会员国的优先事项。提供该地区麻疹和风疹的最新流行病学状况,我们审查了国家监测机构每月提交的2023年这两种疾病的监测数据.我们分析了2023年按年龄组划分的麻疹和风疹病例,案例分类,疫苗接种,住院治疗,以及进口状况和报告与麻疹相关的死亡。2023年,60,860例麻疹病例,包括13例死亡病例,在41个国家报告。大多数病例(95%;n=57,584)由六个国家报告:阿塞拜疆,哈萨克斯坦,吉尔吉斯斯坦,罗马尼亚,俄罗斯联邦,还有Türkiye.在60,848例有年龄数据的病例中,1-4岁为19,137(31%),5-9岁为12,838(21%)。共有10,412(17%)的年龄在20岁以上。该区域中鉴定的基因型主要由D8变体(n=1357)主导,其余为B3变体(n=221)。2023年,17个国家报告了345例风疹病例,大部分来自波兰,吉尔吉斯斯坦,塔吉克斯坦,蒂尔基耶,和乌克兰。共有262例(76%)被归类为临床兼容,79例(23%)被实验室确认。为了在该地区消除麻疹和风疹,需要恢复政治承诺,以便紧急努力增加疫苗接种覆盖率,改善监测和疫情准备,并立即对疫情做出反应。
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