关键词: UV rays antioxidants grape marc photoprotection polyphenols sunburn sunscreen

Mesh : Sunscreening Agents / chemistry pharmacology Vitis / chemistry Plant Extracts / chemistry pharmacology Antioxidants / chemistry pharmacology Cosmetics / chemistry Polyphenols / chemistry pharmacology Wine / analysis Biological Products / chemistry pharmacology Sun Protection Factor

来  源:   DOI:10.3390/molecules29122775   PDF(Pubmed)

Abstract:
Grape marc is a by-product resulting from the winemaking industry that still contains beneficial compounds that can be valorized. Thus, we report here the possibility of using polyphenolic extracts of grape marc origin to obtain sun protection creams. The extractions were performed in ethanol and acetone solutions using pomace from different grape varieties (Merlot, Bläufrankisch, Fetească Neagră, Isabella) as a raw material. The obtained extracts were analyzed in order to determine the total phenolic content, the antioxidant activity, and the sun protection factor (SPF) via Mansur spectrophotometric assay. The best results were achieved using 70% ethanol in water as a solvent. The extracts with the highest potential photoprotective effects are from the Merlot variety (SPFspectrophotometric = 7.83 ± 0.76). The sunscreens were prepared using the 70% ethanolic extract of the Merlot variety evaporated to dryness, redissolved in either distilled water or ethanol. The SPF estimated in vitro via the COLIPA method showed values of 14.07 ± 1.50 and 11.46 ± 1.32 for the aqueous and ethanolic extracts, respectively, when working with a cream to polyphenolic extract a ratio of 1/1 (w/w). At the same time, the use of aqueous polyphenolic extracts ensures the better stability of creams compared with the ethanolic ones.
摘要:
葡萄渣是酿酒工业产生的副产品,仍然含有可以增值的有益化合物。因此,我们在这里报告了使用葡萄marc来源的多酚提取物获得防晒霜的可能性。提取是使用来自不同葡萄品种的果渣在乙醇和丙酮溶液中进行的(Merlot,Bläurfrankisch,Feteasc边沿Neagr边沿,伊莎贝拉)作为原料。分析获得的提取物以确定总酚含量,抗氧化活性,并通过Mansur分光光度法测定防晒因子(SPF)。使用在水中的70%乙醇作为溶剂获得了最好的结果。具有最高潜在光保护作用的提取物来自Merlot品种(SPF分光光度=7.83±0.76)。使用蒸发至干燥的Merlot品种的70%乙醇提取物制备防晒剂,重新溶解在蒸馏水或乙醇。通过COLIPA方法在体外估计的SPF显示,水性和乙醇提取物的值为14.07±1.50和11.46±1.32,分别,当使用乳膏与多酚提取物的比例为1/1(w/w)时。同时,与乙醇相比,使用水性多酚提取物确保了乳膏更好的稳定性。
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