PDF(Pubmed)
Abstract：
Reptiles are usually asymptomatic carriers of Salmonella, with the manifestation of typical clinical signs of acute forms in adult and non-immunocompromised animals being considered exceptions. In the present case, an adult male corn snake (Pantherophis guttatus) was found dead due to septic shock 48 h after consuming a feeder mouse purchased online. The snake\'s tissue samples and faeces were cultured for bacteria isolation. Microbiological examinations of the snake and mouse livers revealed the presence of Salmonella enterica subsp. enterica serovar Midway. A whole-genome analysis of these two isolates showed a high correlation between them: they belonged to the strain type ST-357 for the classic MLST scheme and to the strain type ST 171322 for the cgMLST scheme. Also, a virulence gene analysis revealed the presence of stdB and STM3026 genes. This report conveys a case of food-borne salmonellosis in a pet snake, transmitted from a feeder mouse, likely responsible for the snake\'s death due to septic shock. It highlights the relevance of feeder mice as a source of Salmonella infections in snakes and the associated risks to human health.
摘要：
爬行动物通常是沙门氏菌的无症状携带者，在成年和非免疫功能低下的动物中，急性形式的典型临床体征的表现被认为是例外。在目前的情况下,一只成年雄性玉米蛇（Pantherophisguttatus）在食用在线购买的饲养小鼠48小时后，因感染性休克而死亡。培养蛇的组织样品和粪便以进行细菌分离。蛇和小鼠肝脏的微生物学检查显示存在肠沙门氏菌亚种。肠道血清型中途。对这两个分离株的全基因组分析表明，它们之间存在高度相关性：对于经典MLST方案，它们属于ST-357型菌株，对于cgMLST方案，它们属于ST171322型菌株。此外，毒力基因分析显示存在stdB和STM3026基因。这份报告传达了一例宠物蛇的食源性沙门氏菌病，从喂食鼠标传输，可能是蛇因感染性休克而死亡的原因。它强调了饲养小鼠作为蛇中沙门氏菌感染来源的相关性以及对人类健康的相关风险。
