PDF(Pubmed)
Abstract：
As cancer progresses, patients may experience physical decline, which can impair their ability to carry out essential daily tasks. The aim of this study was to analyze the levels of physical activity in patients with advanced cancer undergoing systemic treatment and its relationship with sociodemographic, clinical, and psychological factors. A prospective, cross-sectional, multicenter study was carried out in 15 oncology departments in Spain. Patients with locally advanced, unresectable, or metastatic cancer who were candidates for systemic treatment were included. Participants completed demographic information and psychological scales. In total, 508 patients were included in the study, the majority of whom were male, over the age of 65, and diagnosed with bronchopulmonary tumors (36%) and metastatic disease. Based on their physical activity levels, participants were categorized as sedentary (20%, n = 190), engaging in light physical activity (43%, n = 412), or demonstrating moderate physical activity (37%, n = 351). Patients who were over 65 years old; had a worse baseline status (ECOG ≥ 1); lacked a partner; had a lower educational level; or were retired or unemployed were found to have lower levels of physical activity. Those with sedentary physical activity reported higher levels of psychological distress, anxiety, depression, somatization, and physical symptoms, as well as worse functional status, global health status, and well-being. Understanding the complex interplay between physical activity and sociodemographic, clinical, and psychological factors can help neuroscientists develop tailored exercise interventions that address the unique needs of advanced cancer patients.
摘要：
随着癌症的进展,患者可能会出现身体衰退，这会削弱他们执行基本日常任务的能力。这项研究的目的是分析接受全身治疗的晚期癌症患者的身体活动水平及其与社会人口统计学的关系。临床,和心理因素。一个潜在的，横截面,在西班牙的15个肿瘤科进行了多中心研究。局部晚期患者，不可切除,纳入了作为全身治疗候选人的转移性癌症.参与者完成了人口统计信息和心理量表。总的来说,508名患者被纳入研究，其中大多数是男性，65岁以上，诊断为支气管肺肿瘤（36％）和转移性疾病。根据他们的体力活动水平，参与者被归类为久坐(20%，n=190),从事轻度体力活动(43%，n=412),或表现出适度的体力活动(37%，n=351）。65岁以上的患者；基线状态较差（ECOG≥1）；缺乏伴侣；受教育程度较低；退休或失业的患者被发现体力活动水平较低。那些久坐不动的身体活动的人报告了更高水平的心理困扰，焦虑,抑郁症,躯体化，和身体症状，以及更差的功能状态，全球健康状况,和幸福。理解身体活动和社会人口统计学之间复杂的相互作用，临床,和心理因素可以帮助神经科学家开发量身定制的运动干预措施，以满足晚期癌症患者的独特需求。
