PDF(Pubmed)
Abstract：
R4Alz is utilized for the early detection of minor neurocognitive disorders. It was designed to assess three main dimensions of cognitive-control abilities: working-memory capacity, attentional control, and executive functioning.
OBJECTIVE: To reveal the cognitive-control dimensions that can differentiate between adults and older adults with healthy cognition, people with subjective cognitive impairment, and people diagnosed with mild cognitive impairment by examining the factorial structure of the R4Alz tool.
METHODS: The study comprised 404 participants: (a) healthy adults (n = 192), (b) healthy older adults (n = 29), (c) people with SCI (n = 74), and (d) people diagnosed with MCI (n = 109). The R4Alz battery was administered to all participants, including tests that assess short-term memory storage, information processing, information updating in working memory, and selective, sustained and divided attention), task/rule-switching, inhibitory control, and cognitive flexibility.
RESULTS: A two-factorial structural model was confirmed for R4Alz, with the first factor representing \"fluid intelligence (FI)\" and the second factor reflecting \"executive functions (EF)\". Both FI and EFs discriminate among all groups.
CONCLUSIONS: The R4Alz battery presents sound construct validity, evaluating abilities in FI and EF. Both abilities can differentiate very early cognitive impairment (SCI) from healthy cognitive aging and MCI.
OBJECTIVE: To reveal the cognitive-control dimensions that can differentiate between adults and older adults with healthy cognition, people with subjective cognitive impairment, and people diagnosed with mild cognitive impairment by examining the factorial structure of the R4Alz tool.
METHODS: The study comprised 404 participants: (a) healthy adults (n = 192), (b) healthy older adults (n = 29), (c) people with SCI (n = 74), and (d) people diagnosed with MCI (n = 109). The R4Alz battery was administered to all participants, including tests that assess short-term memory storage, information processing, information updating in working memory, and selective, sustained and divided attention), task/rule-switching, inhibitory control, and cognitive flexibility.
RESULTS: A two-factorial structural model was confirmed for R4Alz, with the first factor representing \"fluid intelligence (FI)\" and the second factor reflecting \"executive functions (EF)\". Both FI and EFs discriminate among all groups.
CONCLUSIONS: The R4Alz battery presents sound construct validity, evaluating abilities in FI and EF. Both abilities can differentiate very early cognitive impairment (SCI) from healthy cognitive aging and MCI.
摘要：
R4Alz用于轻微神经认知障碍的早期检测。它旨在评估认知控制能力的三个主要维度：工作记忆能力，注意控制，和执行功能。
目的：为了揭示可以区分具有健康认知的成年人和老年人的认知控制维度，有主观认知障碍的人，以及通过检查R4Alz工具的阶乘结构被诊断为轻度认知障碍的人。
方法：该研究包括404名参与者：（a）健康成年人（n=192），（b）健康的老年人（n=29），（c）SCI患者（n=74），和(d)被诊断为MCI的人(n=109)。所有参与者都接受了R4Alz电池，包括评估短期记忆存储的测试，信息处理,工作记忆中的信息更新，选择性,持续和分散的注意力)，任务/规则切换，抑制控制，和认知灵活性。
结果：确认了R4Alz的两因子结构模型，第一个因素代表“流体智力(FI)”，第二个因素反映“执行功能(EF)”。FI和EF在所有群体中都有区别。
结论：R4Alz电池具有良好的结构有效性，评估FI和EF的能力。两种能力都可以将非常早期的认知障碍（SCI）与健康的认知衰老和MCI区分开。
目的：为了揭示可以区分具有健康认知的成年人和老年人的认知控制维度，有主观认知障碍的人，以及通过检查R4Alz工具的阶乘结构被诊断为轻度认知障碍的人。
方法：该研究包括404名参与者：（a）健康成年人（n=192），（b）健康的老年人（n=29），（c）SCI患者（n=74），和(d)被诊断为MCI的人(n=109)。所有参与者都接受了R4Alz电池，包括评估短期记忆存储的测试，信息处理,工作记忆中的信息更新，选择性,持续和分散的注意力)，任务/规则切换，抑制控制，和认知灵活性。
结果：确认了R4Alz的两因子结构模型，第一个因素代表“流体智力(FI)”，第二个因素反映“执行功能(EF)”。FI和EF在所有群体中都有区别。
结论：R4Alz电池具有良好的结构有效性，评估FI和EF的能力。两种能力都可以将非常早期的认知障碍（SCI）与健康的认知衰老和MCI区分开。
