PDF(Pubmed)
Abstract：
OBJECTIVE: This study aimed to compare the remineralization effects of a calcium silicate-based cement (Biodentine) and of a glass ionomer cement (GIC: Fuji IX) on artificially demineralized dentin.
METHODS: Four standard cavities were prepared in dentin discs prepared from 34 extracted sound human third molars. In each disc, one cavity was covered with an acid-resistant varnish before demineralization (Group 1). The specimens were soaked in a chemical demineralization solution for 96 h to induce artificial carious lesions. Thereafter, one cavity each was filled with Biodentine (Group 2) and GIC (Group 3), respectively, and one carious lesion was left unrestored as a negative control (Group 4). Next, specimens were immersed in simulated body fluid (SBF) for 21 days. After cross-sectioning the specimens, the Ca/P ratio was calculated in each specimen by using scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDX). Finally, data were analyzed using repeated-measures ANOVA with post-hoc Bonferroni correction.
RESULTS: Both cement types induced dentin remineralization as compared to Group 4. The Ca/P ratio was significantly higher in Group 2 than in Group 3 (p < 0.05).
CONCLUSIONS: The dentin lesion remineralization capability of Biodentine is higher than that of GIC, suggesting the usefulness of the former as a bioactive dentin replacement material.
CONCLUSIONS: Biodentine has a higher remineralization ability than that of GIC for carious dentin, and its interfacial properties make it a promising bioactive dentin restorative material.
METHODS: Four standard cavities were prepared in dentin discs prepared from 34 extracted sound human third molars. In each disc, one cavity was covered with an acid-resistant varnish before demineralization (Group 1). The specimens were soaked in a chemical demineralization solution for 96 h to induce artificial carious lesions. Thereafter, one cavity each was filled with Biodentine (Group 2) and GIC (Group 3), respectively, and one carious lesion was left unrestored as a negative control (Group 4). Next, specimens were immersed in simulated body fluid (SBF) for 21 days. After cross-sectioning the specimens, the Ca/P ratio was calculated in each specimen by using scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDX). Finally, data were analyzed using repeated-measures ANOVA with post-hoc Bonferroni correction.
RESULTS: Both cement types induced dentin remineralization as compared to Group 4. The Ca/P ratio was significantly higher in Group 2 than in Group 3 (p < 0.05).
CONCLUSIONS: The dentin lesion remineralization capability of Biodentine is higher than that of GIC, suggesting the usefulness of the former as a bioactive dentin replacement material.
CONCLUSIONS: Biodentine has a higher remineralization ability than that of GIC for carious dentin, and its interfacial properties make it a promising bioactive dentin restorative material.
摘要：
目的：本研究旨在比较硅酸钙基水泥（Biodentine）和玻璃离聚物水泥（GIC：FujiIX）对人工脱矿质牙本质的再矿化作用。
方法：在从34个提取的有声人类第三磨牙制备的牙本质盘中制备四个标准腔。在每个光盘中，在去盐之前用耐酸清漆覆盖一个空腔(第1组)。将标本浸泡在化学去矿质溶液中96小时，以诱发人工龋齿病变。此后,每个腔填充生物牙本质（第2组）和GIC（第3组），分别,一个龋齿病变未恢复作为阴性对照（第4组）。接下来,将标本浸入模拟体液（SBF）中21天。在对标本进行横切后,通过使用扫描电子显微镜-能量色散X射线光谱（SEM-EDX）计算每个样品中的Ca/P比。最后,使用重复测量方差分析和事后Bonferroni校正对数据进行分析.
结果:与第4组相比,两种水泥类型均诱导牙本质再矿化。第2组的Ca/P比显著高于第3组(p<0.05)。
结论：Biodentine的牙本质病变再矿化能力高于GIC，表明前者作为生物活性牙本质替代材料的有用性。
结论：Biodentine对龋齿牙本质的再矿化能力高于GIC，其界面性质使其成为一种有前途的生物活性牙本质修复材料。
方法：在从34个提取的有声人类第三磨牙制备的牙本质盘中制备四个标准腔。在每个光盘中，在去盐之前用耐酸清漆覆盖一个空腔(第1组)。将标本浸泡在化学去矿质溶液中96小时，以诱发人工龋齿病变。此后,每个腔填充生物牙本质（第2组）和GIC（第3组），分别,一个龋齿病变未恢复作为阴性对照（第4组）。接下来,将标本浸入模拟体液（SBF）中21天。在对标本进行横切后,通过使用扫描电子显微镜-能量色散X射线光谱（SEM-EDX）计算每个样品中的Ca/P比。最后,使用重复测量方差分析和事后Bonferroni校正对数据进行分析.
结果:与第4组相比,两种水泥类型均诱导牙本质再矿化。第2组的Ca/P比显著高于第3组(p<0.05)。
结论：Biodentine的牙本质病变再矿化能力高于GIC，表明前者作为生物活性牙本质替代材料的有用性。
结论：Biodentine对龋齿牙本质的再矿化能力高于GIC，其界面性质使其成为一种有前途的生物活性牙本质修复材料。
