PDF(Pubmed)
Abstract：
Long-chain polyunsaturated fatty acids (LCPUFA) are of interest due to their potential health properties and have a significant role in reducing the risk of various chronic diseases in humans. It is commonly used as a supplement. However, lipid oxidation is an important negative factor caused by environmental, processing, and limited water solubility of LCPUFA, making them difficult to incorporate into food products. The objective of this research work was to prevent oxidation, extend shelf life, enhance the stability of fatty acids, and to achieve controlled release by preparing spray-dried powder (SDM). For spray-drying, aqueous emulsion blends were formulated using a 1:1 ratio of chia seed oil (CSO) and fish oil (FO) and using a laboratory-scale spray-dryer with varying conditions: inlet air temperature (IAT, 125-185 °C), wall material (WM, 5-25%), pump speed (PS, 3-7 mL/min), and needle speed (NS, 3-11 s). The maximum alpha-linolenic acid (ALA) content was 33 ± 1%. The highest values of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the microcapsules were 8.4 ± 0.4 and 13 ± 1%, respectively. Fourier transform infrared and X-Ray diffraction analysis results indicated that SDM was successfully formulated with Gum Arabic and maltodextrin (MD). The blending without encapsulation of CSO and FO was digested more efficiently and resulted in more oil being released with simulated gastric fluid (SGF), simulated intestinal fluid (SIF), and SGF + SIF conditions without heating. No significant changes were observed for saturated, monounsaturated, and LCPUFA, whether exposed or not to gastrointestinal conditions. However, compared to the release of SDM, it can be useful for designing delivery systems for the controlled release of essential fatty acids.
摘要：
长链多不饱和脂肪酸（LCPUFA）由于其潜在的健康特性而受到关注，并且在降低人类各种慢性疾病的风险方面具有重要作用。它通常用作补充。然而,脂质氧化是由环境引起的重要负面因素，processing,LCPUFA的水溶性有限，使它们难以融入食品中。这项研究工作的目的是防止氧化，延长保质期，增强脂肪酸的稳定性，并通过制备喷雾干燥粉末(SDM)实现控释。对于喷雾干燥，水性乳液混合物使用1:1比例的正大种子油(CSO)和鱼油(FO)并使用实验室规模的喷雾干燥器在不同条件下配制:入口空气温度(IAT,125-185°C),墙体材料(WM，5-25%），泵速(PS,3-7mL/min),和针头速度(NS，3-11s）。最大α-亚麻酸(ALA)含量为33±1%。微胶囊中二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）的最高值分别为8.4±0.4和13±1％，分别。傅里叶变换红外和X射线衍射分析结果表明，SDM与阿拉伯胶和麦芽糖糊精（MD）成功配制。未包封CSO和FO的共混更有效地消化，并导致更多的油被模拟胃液（SGF）释放，模拟肠液（SIF），和SGF+SIF条件下不加热。没有观察到饱和的显着变化，单不饱和,LCPUFA，是否暴露于胃肠道条件。然而,与SDM的发布相比，它可以用于设计用于必需脂肪酸的控释的递送系统。
