关键词: cancer survivors exercise therapy sarcopenia type-specific prevalence

来  源:   DOI:10.5387/fms.23-00019

Abstract:
Sarcopenia is prevalent among 11-25% of adult cancer survivors, depending on the cancer type, although the available data on post-treatment survivors in Japan are limited. If cancer patients develop cachexia, they may experience sustained weight loss as a result, ultimately leading to sarcopenia. Conversely, some patients experience post-treatment weight gain, resulting in sarcopenic obesity. Both sarcopenia and obesity elevate the risk of cardiovascular diseases and mortality; therefore, the importance of sarcopenia prevention and management is undeniable. The Guidelines for Exercise for Cancer Survivors recommend continued physical activity. Recent studies have reported the effectiveness of multimodal interventions, combining pharmacological, nutritional, and exercise approaches, necessitating multidisciplinary care for post-treatment sarcopenia. Innovative health interventions using mobile devices have also gained attention. However, studies on sarcopenia in post-treatment cancer survivors, especially those regarding exercise interventions, remain scarce in Japan, primarily due to limited insurance coverage for such post-treatment interventions and workforce challenges. It is clear that some cancer survivors have sarcopenia, which can lead to worse survival and secondary illness. While the benefits of exercise are clear, a comprehensive approach to sarcopenia is a further challenge for the future.
摘要:
肌肉减少症在11-25%的成年癌症幸存者中普遍存在,根据癌症的类型,尽管日本治疗后幸存者的可用数据有限。如果癌症患者出现恶病质,他们可能会因此经历持续的体重减轻,最终导致肌肉减少症.相反,一些患者在治疗后体重增加,导致肌少症性肥胖。肌肉减少症和肥胖都会增加心血管疾病和死亡率的风险;因此,肌肉减少症的预防和管理的重要性是不可否认的。癌症幸存者运动指南建议继续进行体育锻炼。最近的研究报告了多模式干预的有效性,结合药理学,营养,和锻炼方法,治疗后肌少症需要多学科护理。使用移动设备的创新健康干预措施也受到关注。然而,关于治疗后癌症幸存者的肌肉减少症的研究,特别是那些关于运动干预的,在日本仍然稀缺,主要是由于此类治疗后干预措施和劳动力挑战的保险范围有限。很明显,一些癌症幸存者患有肌少症,这会导致更糟糕的生存率和继发性疾病。虽然锻炼的好处是显而易见的,全面治疗肌少症是未来的进一步挑战。
公众号